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Michio Kurosu

Pharmaceutical Sciences University of Tennessee Health Science Center, Memphis, TN, United States 
Microbiology, anticancer drug discovery, Medicinal Chemistry

Michio Kurosu received his Ph.D. from Osaka University (Japan), School of Pharmaceutical Sciences and broadened postdoctoral training and experience at Harvard University, Department of Chemistry and Chemical Biology. He is a Professor at University of Tennessee Health Science Center. He has a long-term interest in development of new antibacterial agents and anti-cancer drugs.

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Mitachi K, Kansal RG, Hevener KE, et al. (2020) DPAGT1 Inhibitors of Capuramycin Analogues and Their Antimigratory Activities of Solid Tumors. Journal of Medicinal Chemistry
Lelovic N, Mitachi K, Yang J, et al. (2020) Application of Mycobacterium smegmatis as a surrogate to evaluate drug leads against Mycobacterium tuberculosis. The Journal of Antibiotics
Mitachi K, Yun HG, Gillman CD, et al. (2019) Substrate Tolerance of Bacterial Glycosyltransferase MurG: Novel Fluorescence-based Assays. Acs Infectious Diseases
Mitachi K, Kurosu SM, Gillman CD, et al. (2019) A practical synthesis of a novel DPAGT1 inhibitor, aminouridyl phenoxypiperidinbenzyl butanamide (APPB) for in vivo studies. Methodsx. 6: 2305-2321
Mitachi K, Kurosu SM, Eslamimehr S, et al. (2019) Semisynthesis of an Anticancer DPAGT1 Inhibitor from a Muraymycin Biosynthetic Intermediate. Organic Letters. 21: 876-879
Lemieux MR, Siricilla S, Mitachi K, et al. (2018) An antimycobacterial pleuromutilin analogue effective against dormant bacilli. Bioorganic & Medicinal Chemistry
Mitachi K, Yun HG, Kurosu SM, et al. (2018) Novel FR-900493 Analogues That Inhibit the Outgrowth ofSpores. Acs Omega. 3: 1726-1739
Siricilla S, Mitachi K, Yang J, et al. (2017) A New Combination of a Pleuromutilin Derivative and Doxycycline for Treatment of Multidrug-Resistant Acinetobacter baumannii. Journal of Medicinal Chemistry
Yang D, Ding F, Mitachi K, et al. (2016) A Fluorescent Probe for Detecting Mycobacterium tuberculosis and Identifying Genes Critical for Cell Entry. Frontiers in Microbiology. 7: 2021
Mitachi K, Aleiwi BA, Schneider CM, et al. (2016) Stereocontrolled Total Synthesis of Muraymycin D1 Having a Dual Mode of Action against Mycobacterium tuberculosis. Journal of the American Chemical Society
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