Hideyo Yasuda
Area:
Molecular Biolog, Cell Biology
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"Hideyo Yasuda"Bio:
EDUCATION
Bachelor’s degree: Department of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan, 1972.
Master’s degree: Graduate School of University of Tokyo, Japan, 1974. Cell Biology and Molecular Biology.
Ph.D degree: Graduate School of University of Tokyo, Japan, 1977.
Cell Biology and Molecular Biology.
Postgraduate Training
Research Fellowship, Cancer Cell Biology, Roswell Park Memorial Institute, Buffalo, NY, 1982−1983
Research Fellowship, Molecular Biology, School of Medicine, University of California, Davis, CA, 1983−1985
CREDENTIALS
Licensures
1) The activator and method of sumoylation of protein, Japan, JP2001-280645, 2001
2) Poly-ubiquitination of Rb protein catalysed by MDM2, Japan, JP2002-005354, 2002
3) Monoclonal antibody against ISG15 and its application to diagnosis of cancer, Japan, JP2005-300675, 2005
4) Genes related to tumorigenesis of HCV-positive hepatoma, Japan, JP2005- 234915, 2005
5) Wheat having a novel starch and method for producing the same, WO2006/118300, 2006
EXPERIENCE/SERVICE
Academic Appointments
Assistant Professor, Department of Biochemistry and Molecular Biology, Division of Basic Science Research, University of Tokyo, Tokyo, Japan, 1977−1986 Associate Professor, Department of Biochemistry and Molecular Biology, Division of Basic Science Research, Kanazawa University, Kanazawa, Ishikawa, Japan, 1986−1994
Associate Professor, Department of Genetics, Division of Basic Science Research, National Institute of Genetics, Mishima, Shizuoka, Japan, 1988−1994
Professor, Department of Biochemistry and Molecular Biology, Division of Basic Science Research, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan, 1994−2002
Lecturer (Part time), Department of Internal Medicine, Division of Basic Science Research, Gifu University, Gifu, Japan, 2002−2006
Senior Research Scientist, Department of Genetics, The University of Texas
M. D. Anderson Cancer Center, Houston, TX, 4/2007−9/2008
Professor, Department of Genetics, The University of Texas
M. D. Anderson Cancer Center, Houston, TX, 9/2008−12/2012
Professor, Department of Translational Oncology, St. Marianna University School of Medicine, Kanagawa, Japan 1/2013-4/2014
Senior Researcher, Department of Animal Biotechnology (Stem Cell and Regenerating Technology), Konkuk University, Seoul, Korea.
HONORS AND AWARDS
1) Award for Excellent Pharmaceutical Research, The Research Foundation for Pharmaceutical Sciences, 1990
2) Award for Excellent Research for Pharmaceutical Science, The Mochida Memorial Foundation for Medical and Pharmaceutical Sciences, 1996
3) Award for Excellent Pharmaceutical Research, The Research Foundation for Pharmaceutical Sciences, 1997
4) Award for Scientific Research, The Naito Foundation, 1998
5) Award for Excellent Cancer Research, The SAGAWA Foundation for Promotion of Cancer Research, 2000
6) Award for Life Science, The Uehara Memorial Foundation, 2003
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Publications
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Jaiswal PK, Aljebali L, Gaumond MH, et al. (2020) Biochemical characteristics of the chondrocyte-enriched SNORC protein and its transcriptional regulation by SOX9. Scientific Reports. 10: 7790 |
Yasuda H, Oh CD, Chen D, et al. (2016) A Novel Regulatory Mechanism of Type II Collagen Expression via a SOX9-Dependent Enhancer in Intron 6. The Journal of Biological Chemistry |
Oh CD, Yasuda H, Zhao W, et al. (2016) SOX9 directly Regulates CTGF/CCN2 Transcription in Growth Plate Chondrocytes and in Nucleus Pulposus Cells of Intervertebral Disc. Scientific Reports. 6: 29916 |
Oh CD, Lu Y, Liang S, et al. (2015) Correction: SOX9 Regulates Multiple Genes in Chondrocytes, Including Genes Encoding ECM Proteins, ECM Modification Enzymes, Receptors, and Transporters. Plos One. 10: e0143156 |
Chen Q, Sinha K, Deng JM, et al. (2015) Mesenchymal Deletion of Histone Demethylase NO66 in Mice Promotes Bone Formation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research |
Oh CD, Lu Y, Liang S, et al. (2014) SOX9 regulates multiple genes in chondrocytes, including genes encoding ECM proteins, ECM modification enzymes, receptors, and transporters. Plos One. 9: e107577 |
Sinha KM, Yasuda H, Zhou X, et al. (2014) Osterix and NO66 histone demethylase control the chromatin of Osterix target genes during osteoblast differentiation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 29: 855-65 |
Hattori T, Kishino T, Stephen S, et al. (2013) E6-AP/UBE3A protein acts as a ubiquitin ligase toward SOX9 protein. The Journal of Biological Chemistry. 288: 35138-48 |
Chen Q, Liu W, Sinha KM, et al. (2013) Identification and characterization of microRNAs controlled by the osteoblast-specific transcription factor Osterix. Plos One. 8: e58104 |
Coustry F, Oh CD, Hattori T, et al. (2010) The dimerization domain of SOX9 is required for transcription activation of a chondrocyte-specific chromatin DNA template. Nucleic Acids Research. 38: 6018-28 |
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