Steven S. Plotkin
Affiliations: | Department of Physics and Astronomy | University of British Columbia, Vancouver, Vancouver, BC, Canada |
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Parents
Sign in to add mentor| Peter G. Wolynes | grad student | Rice University | |
| José Nelson Onuchic | post-doc | Rice University |
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Publications
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| Garg P, Semmler S, Baudouin C, et al. (2022) Misfolding-Associated Exposure of Natively Buried Residues in Mutant SOD1 Facilitates Binding to TRAF6. Journal of Molecular Biology. 167697 |
| Hsueh SCC, Nijland M, Peng X, et al. (2022) First Principles Calculation of Protein-Protein Dimer Affinities of ALS-Associated SOD1 Mutants. Frontiers in Molecular Biosciences. 9: 845013 |
| Semmler S, Gagné M, Garg P, et al. (2020) TNF receptor associated factor 6 interacts with ALS-linked misfolded superoxide dismutase 1 and promotes aggregation. The Journal of Biological Chemistry |
| McAlary L, Plotkin SS, Yerbury JJ, et al. (2019) Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis. Frontiers in Molecular Neuroscience. 12: 262 |
| Farrawell NE, Yerbury MR, Plotkin SS, et al. (2019) CuATSM Protects Against the In Vitro Cytotoxicity of Wild-Type-Like Copper-Zinc Superoxide Dismutase Mutants but not Mutants That Disrupt Metal Binding. Acs Chemical Neuroscience. 10: 1555-1564 |
| Peng X, Cashman NR, Plotkin SS. (2018) Prediction of Misfolding-Specific Epitopes in SOD1 Using Collective Coordinates. The Journal of Physical Chemistry. B |
| Habibi M, Rottler J, Plotkin SS. (2017) The unfolding mechanism of monomeric mutant SOD1 by simulated force spectroscopy. Biochimica Et Biophysica Acta. Proteins and Proteomics. 1865: 1631-1642 |
| Mills EA, Plotkin SS. (2013) Density functional theory for protein transfer free energy. The Journal of Physical Chemistry. B. 117: 13278-90 |
| Das A, Plotkin SS. (2013) SOD1 exhibits allosteric frustration to facilitate metal binding affinity. Proceedings of the National Academy of Sciences of the United States of America. 110: 3871-6 |
| Das A, Plotkin SS. (2013) Mechanical probes of SOD1 predict systematic trends in metal and dimer affinity of ALS-associated mutants. Journal of Molecular Biology. 425: 850-74 |