Diarmaid Hughes
Affiliations: | Department of Cell and Molecular Biology | Uppsala University, Uppsala, Uppsala län, Sweden |
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| Huseby DL, Cao S, Zamaratski E, et al. (2024) Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria. Proceedings of the National Academy of Sciences of the United States of America. 121: e2317274121 |
| Brandis G, Granström S, Leber AT, et al. (2020) Mutant RNA polymerase can reduce susceptibility to antibiotics via ppGpp-independent induction of a stringent-like response. The Journal of Antimicrobial Chemotherapy |
| Praski Alzrigat L, Huseby DL, Brandis G, et al. (2020) Resistance/fitness trade-off is a barrier to the evolution of MarR inactivation mutants in Escherichia coli. The Journal of Antimicrobial Chemotherapy |
| Nord C, Bjerketorp J, Levenfors JJ, et al. (2020) Isopedopeptins A-H: Cationic Cyclic Lipodepsipeptides from UP508 Targeting WHO Top-Priority Carbapenem-Resistant Bacteria. Acs Chemical Biology |
| Garoff L, Pietsch F, Huseby DL, et al. (2020) Population bottlenecks strongly influence the evolutionary trajectory to fluoroquinolone resistance in Escherichia coli. Molecular Biology and Evolution |
| Huseby DL, Brandis G, Praski Alzrigat L, et al. (2020) Antibiotic resistance by high-level intrinsic suppression of a frameshift mutation in an essential gene. Proceedings of the National Academy of Sciences of the United States of America |
| Juhas M, Widlake E, Teo J, et al. (2019) In vitro activity of apramycin against multidrug-, carbapenem- and aminoglycoside-resistant Enterobacteriaceae and Acinetobacter baumannii. The Journal of Antimicrobial Chemotherapy |
| Vestö K, Huseby DL, Snygg I, et al. (2018) Muramyl Endopeptidase Spr Contributes to Intrinsic Vancomycin Resistance in Serovar Typhimurium. Frontiers in Microbiology. 9: 2941 |
| Brandis G, Hughes D. (2018) Mechanisms of fitness cost reduction for rifampicin-resistant strains with deletion or duplication mutations in rpoB. Scientific Reports. 8: 17488 |
| Pantel L, Florin T, Dobosz-Bartoszek M, et al. (2018) Odilorhabdins, Antibacterial Agents that Cause Miscoding by Binding at a New Ribosomal Site. Molecular Cell. 70: 83-94.e7 |