Abhigyan Satyam

Affiliations: 
Harvard Medical School (Beth Israel Deaconess Medical Center) 
Area:
complement activation, macromolecular crowding, tissue engineering, podocytes
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"Abhigyan Satyam"
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Katsuyama E, Humbel M, Suarez-Fueyo A, et al. (2024) CD38 in SLE CD4 T cells promotes Ca flux and suppresses interleukin-2 production by enhancing the expression of GM2 on the surface membrane. Nature Communications. 15: 8304
Umeda M, Karino K, Satyam A, et al. (2024) Hypoxia Promotes the Expression of ADAM9 by Tubular Epithelial Cells, Which Enhances Transforming Growth Factor β1 Activation and Promotes Tissue Fibrosis in Patients With Lupus Nephritis. Arthritis & Rheumatology (Hoboken, N.J.)
Schmauch E, Severin Y, Xing X, et al. (2024) Targeting IL-1 controls refractory pityriasis rubra pilaris. Science Advances. 10: eado2365
Koga T, Umeda M, Yoshida N, et al. (2022) Inhibition of calcium/calmodulin-dependent protein kinase IV in arthritis: Dual effect on Th17 cell activation and osteoclastogenesis. Rheumatology (Oxford, England)
Chen PM, Katsuyama E, Satyam A, et al. (2022) CD38 reduces mitochondrial fitness and cytotoxic T cell response against viral infection in lupus patients by suppressing mitophagy. Science Advances. 8: eabo4271
Satyam A, Hisada R, Bhargava R, et al. (2022) Intertwined pathways of complement activation command the pathogenesis of lupus nephritis. Translational Research : the Journal of Laboratory and Clinical Medicine
Jamaly S, Tsokos MG, Bhargava R, et al. (2021) Complement activation and increased expression of Syk, mucin-1 and CaMK4 in kidneys of patients with COVID-19. Clinical Immunology (Orlando, Fla.). 229: 108795
Satyam A, Tsokos MG, Brook OR, et al. (2021) Activation of classical and alternative complement pathways in the pathogenesis of lung injury in COVID-19. Clinical Immunology (Orlando, Fla.). 226: 108716
Satyam A, Tsokos MG, Tresback JS, et al. (2020) Cell‐Derived Extracellular Matrix‐Rich Biomimetic Substrate Supports Podocyte Proliferation, Differentiation, and Maintenance of Native Phenotype Advanced Functional Materials. 30
Kost-Alimova M, Sidhom EH, Satyam A, et al. (2020) A High-Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury. Cell Reports. Medicine. 1: 100137
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