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Nick Alex Saccomano

Array Biopharma 
ONcology drug discovery
"Nick Saccomano"
Mean distance: 7.5
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Sanguinetti MC, Johnson JH, Hammerland LG, et al. (1997) Heteropodatoxins: peptides isolated from spider venom that block Kv4.2 potassium channels. Molecular Pharmacology. 51: 491-8
Heck SD, Faraci WS, Kelbaugh PR, et al. (1996) Posttranslational amino acid epimerization: enzyme-catalyzed isomerization of amino acid residues in peptide chains. Proceedings of the National Academy of Sciences of the United States of America. 93: 4036-9
Heck SD, Siok CJ, Krapcho KJ, et al. (1994) Functional consequences of posttranslational isomerization of ser46 in a calcium channel toxin Science. 266: 1065-1068
Saccomano NA, Ahlijanian MK. (1994) Ca2+ channel toxins: Tools to study channel structure and function Drug Development Research. 33: 319-343
Heck SD, Kelbaugh PR, Kelly ME, et al. (1994) Disulfide bond assignment of ω-agatoxins IVB and IVC: Discovery of a D-serine residue in ω-agatoxin IVB Journal of the American Chemical Society. 116: 10426-10436
Heck SD, Siok CJ, Kelbaugh PR, et al. (1994) Correction: Functional consequences of post-translational isomerization of Ser46 in a calcium channel toxin (Science (1994) 11 Nov (1065)) Science. 266: 1464
Yu H, Rosen MK, Saccomano NA, et al. (1993) Sequential assignment and structure determination of spider toxin omega-Aga-IVB. Biochemistry. 32: 13123-9
Meltz M, Saccomano NA. (1992) Lipase mediated optical resolution of bicyclic secondary carbinols Tetrahedron Letters. 33: 1201-1202
John Jasys V, Kelbaugh PR, Nason DM, et al. (1992) Novel quaternary ammonium salt-containing polyamines from the Agelenopsis aperta funnel-web spider Journal of Organic Chemistry. 57: 1814-1820
Saccomano NA, Vinick FJ, Koe BK, et al. (1991) Calcium-independent phosphodiesterase inhibitors as putative antidepressants: [3-(bicycloalkyloxy)-4-methoxyphenyl]-2-imidazolidinones. Journal of Medicinal Chemistry. 34: 291-8
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