Maris A. Cinelli

Affiliations: 
Department of Chemistry Northern Michigan University, Marquette, MI, United States 
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"Maris A. Cinelli"
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https://www.proquest.com/openview/acd3b611ab88fb9f6f24aff536fcbb4a/1

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Parents

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Mark S. Cushman grad student 2011 Purdue
 (Design, synthesis, and biological evaluation of aromathecins, indenoisoquinolines, and related compounds as topoisomerase I inhibitors)
A. Daniel Jones post-doc Michigan State
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Publications

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Cinelli MA, Jones AD. (2021) Alkaloids of the Genus : Review of a Rich Resource for Natural Product Discovery. Molecules (Basel, Switzerland). 26
Cinelli MA, Reidl CT, Li H, et al. (2020) First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate. Journal of Medicinal Chemistry
Nenortas NP, Cinelli MA, Morrell AE, et al. (2018) Activity of aromathecins against African trypanosomes. Antimicrobial Agents and Chemotherapy
Cinelli MA, Li H, Chreifi G, et al. (2017) Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors. Journal of Medicinal Chemistry
Cinelli MA, Li H, Pensa AV, et al. (2015) Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase. Journal of Medicinal Chemistry
Cinelli MA, Li H, Chreifi G, et al. (2014) Simplified 2-aminoquinoline-based scaffold for potent and selective neuronal nitric oxide synthase inhibition Journal of Medicinal Chemistry. 57: 1513-1530
Cinelli MA, Reddy PV, Lv PC, et al. (2012) Identification, synthesis, and biological evaluation of metabolites of the experimental cancer treatment drugs indotecan (LMP400) and indimitecan (LMP776) and investigation of isomerically hydroxylated indenoisoquinoline analogues as topoisomerase I poisons. Journal of Medicinal Chemistry. 55: 10844-62
Peterson KE, Cinelli MA, Morrell AE, et al. (2011) Alcohol-, diol-, and carbohydrate-substituted indenoisoquinolines as topoisomerase I inhibitors: investigating the relationships involving stereochemistry, hydrogen bonding, and biological activity. Journal of Medicinal Chemistry. 54: 4937-53
Marler L, Conda-Sheridan M, Cinelli MA, et al. (2010) Cancer chemopreventive potential of aromathecins and phenazines, novel natural product derivatives. Anticancer Research. 30: 4873-82
Cinelli MA, Morrell AE, Dexheimer TS, et al. (2010) The structure-activity relationships of A-ring-substituted aromathecin topoisomerase I inhibitors strongly support a camptothecin-like binding mode. Bioorganic & Medicinal Chemistry. 18: 5535-52
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