André Mann
Affiliations: | School of Pharmacy Strasbourg |
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Parents
Sign in to add mentor| Ian Fleming | grad student | Cambridge | |
| Camille-Georges Wermuth | grad student | School of Pharmacy Strasbourg |
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Publications
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| Hounsou C, Baehr C, Gasparik V, et al. (2017) From the Promiscuous Asenapine to Potent Fluorescent Ligands Acting at a Series of Aminergic G Protein Coupled Receptors. Journal of Medicinal Chemistry |
| Hoch L, Faure H, Roudaut H, et al. (2015) MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1817-29 |
| Hounsou C, Margathe JF, Oueslati N, et al. (2015) Time-resolved FRET binding assay to investigate hetero-oligomer binding properties: proof of concept with dopamine D1/D3 heterodimer. Acs Chemical Biology. 10: 466-74 |
| Gorojankina T, Hoch L, Faure H, et al. (2013) Discovery, molecular and pharmacological characterization of GSA-10, a novel small-molecule positive modulator of Smoothened. Molecular Pharmacology. 83: 1020-9 |
| Solinas A, Faure H, Roudaut H, et al. (2012) Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity. Journal of Medicinal Chemistry. 55: 1559-71 |
| Cazorla M, Prémont J, Mann A, et al. (2011) Identification of a low-molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice. The Journal of Clinical Investigation. 121: 1846-57 |
| Roudaut H, Traiffort E, Gorojankina T, et al. (2011) Identification and mechanism of action of the acylguanidine MRT-83, a novel potent Smoothened antagonist. Molecular Pharmacology. 79: 453-60 |
| Manetti F, Faure H, Roudaut H, et al. (2010) Virtual screening-based discovery and mechanistic characterization of the acylthiourea MRT-10 family as smoothened antagonists. Molecular Pharmacology. 78: 658-65 |
| Masdeu C, Faure H, Coulombe J, et al. (2006) Identification and characterization of Hedgehog modulator properties after functional coupling of Smoothened to G15. Biochemical and Biophysical Research Communications. 349: 471-9 |
| Hackling A, Ghosh R, Perachon S, et al. (2003) N-(omega-(4-(2-methoxyphenyl)piperazin-1-yl)alkyl)carboxamides as dopamine D2 and D3 receptor ligands. Journal of Medicinal Chemistry. 46: 3883-99 |