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Nihal Tugcu, Ph.D.

Affiliations: 
2002 Rensselaer Polytechnic Institute, Troy, NY, United States 
Area:
Chemical Engineering
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"Nihal Tugcu"
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Steven M. Cramer grad student 2002 RPI
 (Design of high affinity low molecular weight displacers and investigation of the selectivity of displacers and proteins in ion exchange systems.)

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Publications

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Coffman J, Marques B, Orozco R, et al. (2020) Highland Games: A benchmarking exercise in predicting biophysical and drug properties of monoclonal antibodies from amino acid sequences. Biotechnology and Bioengineering
Tugcu N. (2008) Purification of proteins using displacement chromatography. Methods in Molecular Biology (Clifton, N.J.). 421: 71-89
Tugcu N, Roush DJ, Göklen KE. (2008) Maximizing productivity of chromatography steps for purification of monoclonal antibodies. Biotechnology and Bioengineering. 99: 599-613
Rege K, Ladiwala A, Tugcu N, et al. (2004) Parallel screening of selective and high-affinity displacers for proteins in ion-exchange systems. Journal of Chromatography. A. 1033: 19-28
Tugcu N, Ladiwala A, Breneman CM, et al. (2003) Identification of chemically selective displacers using parallel batch screening experiments and quantitative structure efficacy relationship models. Analytical Chemistry. 75: 5806-16
Tugcu N, Song M, Breneman CM, et al. (2003) Prediction of the effect of mobile-phase salt type on protein retention and selectivity in anion exchange systems. Analytical Chemistry. 75: 3563-72
Song M, Breneman CM, Bi J, et al. (2002) Prediction of protein retention times in anion-exchange chromatography systems using support vector regression. Journal of Chemical Information and Computer Sciences. 42: 1347-57
Tugcu N, Bae SS, Moore JA, et al. (2002) Stationary phase effects on the dynamic affinity of low-molecular-mass displacers. Journal of Chromatography. A. 954: 127-35
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