Frank Hahn

Affiliations: 
2011-2015 Leibniz Universität Hannover, Hannover, Lower Saxony, Germany 
 2016- University of Bayreuth 
Area:
Natural products research / Biocatalysis
Website:
http://www.oc-hahn.uni-bayreuth.de/de/index.html
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Publications

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Wunderlich J, Roß T, Schröder M, et al. (2020) Step-Economic Synthesis of Biomimetic β-Ketopolyene Thioesters and Demonstration of Their Usefulness in Enzymatic Biosynthesis Studies. Organic Letters. 22: 4955-4959
Hahn F, Guth FM. (2020) The ambruticins and jerangolids - chemistry, biology and chemoenzymatic synthesis of potent antifungal drug candidates. Natural Product Reports
Hollmann T, Berkhan G, Wagner L, et al. (2020) Biocatalysts from Biosynthetic Pathways: Enabling Stereoselective, Enzymatic Cycloether Formation on a Gram Scale Acs Catalysis. 10: 4973-4982
Lindner F, Friedrich S, Hahn F. (2018) Total Synthesis of Complex Biosynthetic Late-Stage Intermediates and Bioconversion by a Tailoring Enzyme from Jerangolid Biosynthesis. The Journal of Organic Chemistry
Sung KH, Berkhan G, Hollmann T, et al. (2017) Insights into the dual Activity of a Bifunctional Dehydratase-Cyclase Domain. Angewandte Chemie (International Ed. in English)
Friedrich S, Hemmerling F, Lindner F, et al. (2016) Characterisation of the Broadly-Specific O-Methyl-transferase JerF from the Late Stages of Jerangolid Biosynthesis. Molecules (Basel, Switzerland). 21
Berkhan G, Merten C, Holec C, et al. (2016) The Interplay between a Multifunctional Dehydratase Domain and a C-Methyltransferase Effects Olefin Shift in Ambruticin Biosynthesis. Angewandte Chemie (International Ed. in English)
Hemmerling F, Hahn F. (2016) Biosynthesis of oxygen and nitrogen-containing heterocycles in polyketides. Beilstein Journal of Organic Chemistry. 12: 1512-50
Friedrich S, Hahn F. (2015) Opportunities for enzyme catalysis in natural product chemistry Tetrahedron. 71: 1473-1508
Berkhan G, Hahn F. (2014) A dehydratase domain in ambruticin biosynthesis displays additional activity as a Pyran-forming Cyclase Angewandte Chemie - International Edition. 53: 14240-14244
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