Joshua Lewis

Affiliations: 
Biomedical Engineering Georgia Institute of Technology and Emory University, Atlanta, GA, United States 
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Ji Z, Moore J, Devarie-Baez NO, et al. (2023) Redox integration of signaling and metabolism in a head and neck cancer model of radiation resistance using COSM. Frontiers in Oncology. 12: 946320
Lewis JE, Kemp ML. (2021) Integration of machine learning and genome-scale metabolic modeling identifies multi-omics biomarkers for radiation resistance. Nature Communications. 12: 2700
Lewis JE, Forshaw TE, Boothman DA, et al. (2021) Personalized Genome-Scale Metabolic Models Identify Targets of Redox Metabolism in Radiation-Resistant Tumors. Cell Systems. 12: 68-81.e11
Shukla K, Singh N, Lewis JE, et al. (2020) MTHFD2 Blockade Enhances the Efficacy of β-Lapachone Chemotherapy With Ionizing Radiation in Head and Neck Squamous Cell Cancer. Frontiers in Oncology. 10: 536377
Paudel BB, Lewis JE, Hardeman KN, et al. (2020) An Integrative Gene Expression and Mathematical Flux Balance Analysis Identifies Targetable Redox Vulnerabilities in Melanoma Cells. Cancer Research. 80: 4565-4577
Forshaw TE, Holmila R, Nelson KJ, et al. (2019) Peroxiredoxins in Cancer and Response to Radiation Therapies. Antioxidants (Basel, Switzerland). 8
Lewis JE, Singh N, Holmila RJ, et al. (2019) Targeting NAD Metabolism to Enhance Radiation Therapy Responses. Seminars in Radiation Oncology. 29: 6-15
Lewis JE, Costantini F, Mims J, et al. (2017) Genome-scale modeling of NADPH-driven β-lapachone sensitization in head and neck squamous cell carcinoma. Antioxidants & Redox Signaling
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