Joseph J. Falke, Ph.D.

Affiliations: 
1987- Chemistry & Biophysics University of Colorado, Boulder, Boulder, CO, United States 
Area:
chemosensory pathways
Website:
http://spot.colorado.edu/~falke/FalkeBio.html
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"Joseph Falke"
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SNBCP

Parents

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Sunney I. Chan grad student 1979-1984 Caltech
 (The behavior and structure of the band 3 anion transport site: A 35Cl and 37Cl NMR study.)
Daniel E. Koshland post-doc 1985-1987 UC Berkeley

Children

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Claire Careaga grad student 1993 CU Boulder
Steve Chervitz grad student 1990-1995 CU Boulder
Steve Drake grad student 1996 CU Boulder
Randal Bass grad student 1998 CU Boulder
Scott Butler grad student 1998 CU Boulder
Joshua Bornhorst grad student 2002 CU Boulder
Susy C. Kohout grad student 2002 CU Boulder (Neurotree)
Nathan Malmberg grad student 2004 CU Boulder
Aaron Miller grad student 2006 CU Boulder
Kyle Landgraf grad student 2009 CU Boulder
Ka Lin Swain grad student 2010 CU Boulder
Pete Slivka grad student 2012 CU Boulder
John Corbin post-doc XOMA Inc
Annette Erbse post-doc CU Boulder
Jefferson Knight post-doc UC Denver
Linda A. Luck post-doc Clarkson University
Eric Nalefski post-doc US Genomics
Olve B. Peersen post-doc Colorado State
Kene N. Piasta post-doc Brandeis
Jefferson D. Knight post-doc 2006-2010 CU Boulder
BETA: Related publications

Publications

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Ziemba BP, Falke JJ. (2018) A PKC-MARCKS-PI3K regulatory module links Ca2+ and PIP3 signals at the leading edge of polarized macrophages. Plos One. 13: e0196678
Buckles TC, Ziemba BP, Masson GR, et al. (2017) Single-Molecule Study Reveals How Receptor and Ras Synergistically Activate PI3Kα and PIP3 Signaling. Biophysical Journal. 113: 2396-2405
Ziemba BP, Swisher GH, Masson G, et al. (2016) Regulation of a Coupled MARCKS-PI3K Lipid Kinase Circuit by Calmodulin: Single-Molecule Analysis of a Membrane-Bound Signaling Module. Biochemistry. 55: 6395-6405
Ziemba BP, Burke JE, Masson G, et al. (2016) Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling Pathway. Biophysical Journal. 110: 1811-25
Parkinson JS, Hazelbauer GL, Falke JJ. (2015) Signaling and sensory adaptation in Escherichia coli chemoreceptors: 2015 update. Trends in Microbiology. 23: 257-66
Falke JJ, Piasta KN. (2014) Architecture and signal transduction mechanism of the bacterial chemosensory array: progress, controversies, and challenges. Current Opinion in Structural Biology. 29: 85-94
Falke JJ. (2014) Piston versus scissors: chemotaxis receptors versus sensor His-kinase receptors in two-component signaling pathways. Structure (London, England : 1993). 22: 1219-20
Piasta KN, Falke JJ. (2014) Increasing and decreasing the ultrastability of bacterial chemotaxis core signaling complexes by modifying protein-protein contacts. Biochemistry. 53: 5592-600
Li J, Ziemba BP, Falke JJ, et al. (2014) Interactions of protein kinase C-α C1A and C1B domains with membranes: a combined computational and experimental study. Journal of the American Chemical Society. 136: 11757-66
Briegel A, Wong ML, Hodges HL, et al. (2014) New insights into bacterial chemoreceptor array structure and assembly from electron cryotomography. Biochemistry. 53: 1575-85
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