Joseph J. Falke, Ph.D.
Affiliations: | 1987- | Chemistry & Biophysics | University of Colorado, Boulder, Boulder, CO, United States |
Area:
chemosensory pathwaysWebsite:
http://spot.colorado.edu/~falke/FalkeBio.htmlGoogle:
"Joseph Falke"Mean distance: 7.65 | S | N | B | C | P |
Parents
Sign in to add mentor| Sunney I. Chan | grad student | 1979-1984 | Caltech | |
| (The behavior and structure of the band 3 anion transport site: A 35Cl and 37Cl NMR study.) | ||||
| Daniel E. Koshland | post-doc | 1985-1987 | UC Berkeley | |
Children
Sign in to add trainee| Claire Careaga | grad student | 1993 | CU Boulder |
| Steve Chervitz | grad student | 1990-1995 | CU Boulder |
| Steve Drake | grad student | 1996 | CU Boulder |
| Randal Bass | grad student | 1998 | CU Boulder |
| Scott Butler | grad student | 1998 | CU Boulder |
| Joshua Bornhorst | grad student | 2002 | CU Boulder |
| Susy C. Kohout | grad student | 2002 | CU Boulder (Neurotree) |
| Nathan Malmberg | grad student | 2004 | CU Boulder |
| Aaron Miller | grad student | 2006 | CU Boulder |
| Kyle Landgraf | grad student | 2009 | CU Boulder |
| Ka Lin Swain | grad student | 2010 | CU Boulder |
| Pete Slivka | grad student | 2012 | CU Boulder |
| John Corbin | post-doc | XOMA Inc | |
| Annette Erbse | post-doc | CU Boulder | |
| Jefferson Knight | post-doc | UC Denver | |
| Linda A. Luck | post-doc | Clarkson University | |
| Eric Nalefski | post-doc | US Genomics | |
| Olve B. Peersen | post-doc | Colorado State | |
| Kene N. Piasta | post-doc | Brandeis | |
| Jefferson D. Knight | post-doc | 2006-2010 | CU Boulder |
BETA: Related publications
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Publications
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| Fleming IR, Hannan JP, Swisher GH, et al. (2022) Binding of active Ras and its mutants to the Ras binding domain of PI-3-kinase: A quantitative approach to K measurements. Analytical Biochemistry. 663: 115019 |
| Gordon MT, Ziemba BP, Falke JJ. (2021) Single-molecule studies reveal regulatory interactions between master kinases PDK1, AKT1, and PKC. Biophysical Journal |
| Hannan JP, Swisher GH, Martyr JG, et al. (2021) HPLC method to resolve, identify and quantify guanine nucleotides bound to recombinant ras GTPase. Analytical Biochemistry. 114338 |
| Swisher GH, Hannan JP, Cordaro NJ, et al. (2021) Ras-Guanine Nucleotide Complexes: A UV Spectral Deconvolution Method to Analyze Protein Concentration, Nucleotide Stoichiometry, and Purity. Analytical Biochemistry. 114066 |
| Buckles TC, Ohashi Y, Tremel S, et al. (2020) Regulation of a Class III PI3K Lipid Kinase (VPS34 Complex II) by the Small G Protein Rab5A: Single Molecule Analysis Reveals a Dual Regulatory Mechanism. Biophysical Journal |
| Gordon MT, Falke JJ. (2020) Direct Detection and Characterization of a Phosphoinositide Dependent Kinase-1 (PDK1) Homodimer on a Target Membrane Surface Via Single Molecule Fluorescence Biophysical Journal. 118 |
| Falke JJ, Ziemba BP, Buckles TC, et al. (2020) Regulatory Mechanisms of Ca2+, Receptor, Ras, and Lipid Signals that Control Actin Polymerization During Cell Migration Biophysical Journal. 118 |
| Ziemba BP, Falke JJ. (2018) A PKC-MARCKS-PI3K regulatory module links Ca2+ and PIP3 signals at the leading edge of polarized macrophages. Plos One. 13: e0196678 |
| Buckles TC, Ziemba BP, Masson GR, et al. (2017) Single-Molecule Study Reveals How Receptor and Ras Synergistically Activate PI3Kα and PIP3 Signaling. Biophysical Journal. 113: 2396-2405 |
| Buckles T, Ziemba B, Burke JE, et al. (2017) Activation of PI3K by Ras: Single Molecule Studies of the Activation Mechanism Biophysical Journal. 112 |