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Axel T Neffe, Prof. Dr. rer. nat.

Affiliations:	2000-2004	Organic Chemistry	University of Hamburg, Hamburg, Hamburg, Germany
	2004-2006	Department of Chemistry	University of Canterbury (New Zealand)
	2006-2018	Biomimetic Materials	Helmholtz-Zentrum Geesthacht
	2018-2020	Technical and Macromolecular Chemistry	University of Hamburg, Hamburg, Hamburg, Germany
	2020-2021		Helmholtz-Zentrum Hereon
	2022-2023	Polymer Chemistry	Helmholtz-Zentrum Hereon
	2023-2024	Sustainable Materials	Helmholtz-Zentrum Hereon
	2024-	Institute of Materials Chemistry	Brandenburg University of Technology Cottbus-Senftenberg

Area:

Chemistry

Website:

https://www.b-tu.de/fg-organische-chemie-polymere

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Parents

Bernd Meyer	grad student	2000-2004
Andrew D. Abell	post-doc	2004-2006	University of Canterbury, New Zealand

Children

Collaborators

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Publications

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Abell AD, Jones MA, Coxon JM, et al. (2009) Molecular modeling, synthesis, and biological evaluation of macrocyclic calpain inhibitors. Angewandte Chemie (International Ed. in English). 48: 1455-8
Jones MA, Morton JD, Coxon JM, et al. (2008) Synthesis, biological evaluation and molecular modelling of N-heterocyclic dipeptide aldehydes as selective calpain inhibitors. Bioorganic & Medicinal Chemistry. 16: 6911-23
Neffe AT, Bilang M, Grüneberg I, et al. (2007) Rational optimization of the binding affinity of CD4 targeting peptidomimetics with potential anti HIV activity. Journal of Medicinal Chemistry. 50: 3482-8
Abell AD, Jones MA, Neffe AT, et al. (2007) Investigation into the P3 binding domain of m-calpain using photoswitchable diazo- and triazene-dipeptide aldehydes: new anticataract agents. Journal of Medicinal Chemistry. 50: 2916-20
Neffe AT, Bilang M, Meyer B. (2006) Synthesis and optimization of peptidomimetics as HIV entry inhibitors against the receptor protein CD4 using STD NMR and ligand docking. Organic & Biomolecular Chemistry. 4: 3259-67
Neffe AT, Abell AD. (2005) Developments in the design and synthesis of calpain inhibitors Current Opinion in Drug Discovery and Development. 8: 684-700
Abell AD, Brown KM, Coxon JM, et al. (2005) Synthesis and evaluation of eight-membered cyclic pseudo-dipeptides Peptides. 26: 251-258
Neffe AT, Meyer B. (2004) A peptidomimetic HIV-entry inhibitor directed against the CD4 binding site of the viral glycoprotein gp120. Angewandte Chemie (International Ed. in English). 43: 2937-40

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