Ettore Appella
Affiliations: | National Cancer Institute, Rockville, MD, United States |
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Publications
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| Tagad HD, Debnath S, Clausse V, et al. (2018) Chemical features important for activity in a class of inhibitors targeting the Wip1 flap subdomain. Chemmedchem |
| Yang Y, Zhu J, Hassink M, et al. (2017) A novel preventive strategy against HIV-1 infection: combinatorial use of inhibitors targeting the nucleocapsid and fusion proteins. Emerging Microbes & Infections. 6: e40 |
| Wallace GS, Cheng-Mayer C, Schito ML, et al. (2009) Human immunodeficiency virus type 1 nucleocapsid inhibitors impede trans infection in cellular and explant models and protect nonhuman primates from infection. Journal of Virology. 83: 9175-82 |
| Jenkins LM, Mazur SJ, Rossi M, et al. (2008) Quantitative proteomics analysis of the effects of ionizing radiation in wild type and p53 K317R knock-in mouse thymocytes. Molecular & Cellular Proteomics : McP. 7: 716-27 |
| Schito ML, Soloff AC, Slovitz D, et al. (2006) Preclinical evaluation of a zinc finger inhibitor targeting lentivirus nucleocapsid protein in SIV-infected monkeys. Current Hiv Research. 4: 379-86 |
| Srivastava P, Schito M, Fattah RJ, et al. (2005) Optimization of unique, uncharged thioesters as inhibitors of HIV replication. Bioorganic & Medicinal Chemistry. 12: 6437-50 |
| Schito ML, Goel A, Song Y, et al. (2003) In vivo antiviral activity of novel human immunodeficiency virus type 1 nucleocapsid p7 zinc finger inhibitors in a transgenic murine model. Aids Research and Human Retroviruses. 19: 91-101 |
| Mauser A, Saito S, Appella E, et al. (2002) The Epstein-Barr virus immediate-early protein BZLF1 regulates p53 function through multiple mechanisms. Journal of Virology. 76: 12503-12 |
| Song Y, Goel A, Basrur V, et al. (2002) Synthesis and biological properties of amino acid amide ligand-based pyridinioalkanoyl thioesters as anti-HIV agents. Bioorganic & Medicinal Chemistry. 10: 1263-73 |
| Goel A, Mazur SJ, Fattah RJ, et al. (2002) Benzamide-based thiolcarbamates: a new class of HIV-1 NCp7 inhibitors. Bioorganic & Medicinal Chemistry Letters. 12: 767-70 |