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Meredith D Hartley, Ph.D.

Affiliations: 
2020- Chemistry University of Kansas, Lawrence, KS, United States 
Area:
Biochemistry, Bioanalytical, Chemical Biology, Neurochemistry
Website:
https://chem.ku.edu/people/meredith-d-hartley
Google:
"Meredith Diane Hartley"
Bio:

Ph.D., Massachusetts Institute of Technology, 2011
Research interest - Lipids in the central nervous system
Hartley, Meredith Diane Polyprenyl-dependent glycan assembly pathways in microbial pathogens Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2011.

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Parents

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Barbara Imperiali grad student 2011 MIT
 (Polyprenyl-dependent glycan assembly pathways in microbial pathogens)

Children

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Nishama De Silva grad student 2019- University of Kansas
Matthew Zupan grad student 2019- University of Kansas
Jenna Williams grad student 2020- University of Kansas
Rashmi Binjawadagi grad student 2021- University of Kansas
Ziyu Zhu grad student 2021- University of Kansas
Disni Dedunupitiya grad student 2022- University of Kansas

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Publications

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De Silva Mohotti N, Kobayashi H, Williams JM, et al. (2023) Lipidomic Analysis Reveals Differences in the Extent of Remyelination in the Brain and Spinal Cord. Journal of Proteome Research
De Silv Mohotti N, Kobayashi H, Williams JM, et al. (2023) Lipidomic analysis reveals differences in the extent of remyelination in the brain and spinal cord. Biorxiv : the Preprint Server For Biology
Hartley MD, Shokat MD, DeBell MJ, et al. (2020) Pharmacological Complementation Remedies an Inborn Error of Lipid Metabolism. Cell Chemical Biology
Hartley MD, Banerji T, Tagge IJ, et al. (2019) Myelin repair stimulated by CNS-selective thyroid hormone action. Jci Insight. 4
Ferrara SJ, Meinig JM, Placzek AT, et al. (2017) Ester-to-amide rearrangement of ethanolamine-derived prodrugs of sobetirome with increased blood-brain barrier penetration. Bioorganic & Medicinal Chemistry
Placzek AT, Ferrara SJ, Hartley MD, et al. (2016) Sobetirome prodrug esters with enhanced blood-brain barrier permeability. Bioorganic & Medicinal Chemistry
Hartley MD, Schneggenburger PE, Imperiali B. (2013) Lipid bilayer nanodisc platform for investigating polyprenol-dependent enzyme interactions and activities. Proceedings of the National Academy of Sciences of the United States of America. 110: 20863-70
Hartley MD, Imperiali B. (2012) At the membrane frontier: a prospectus on the remarkable evolutionary conservation of polyprenols and polyprenyl-phosphates. Archives of Biochemistry and Biophysics. 517: 83-97
Børud B, Viburiene R, Hartley MD, et al. (2011) Genetic and molecular analyses reveal an evolutionary trajectory for glycan synthesis in a bacterial protein glycosylation system. Proceedings of the National Academy of Sciences of the United States of America. 108: 9643-8
Hartley MD, Morrison MJ, Aas FE, et al. (2011) Biochemical characterization of the O-linked glycosylation pathway in Neisseria gonorrhoeae responsible for biosynthesis of protein glycans containing N,N'-diacetylbacillosamine. Biochemistry. 50: 4936-48
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