Ryan Gonciarz

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2018- University of California, San Francisco, San Francisco, CA 
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"Ryan Gonciarz"
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Klope MT, Tapia Cardona JA, Chen J, et al. (2024) Synthesis and In Vivo Profiling of Desymmetrized Antimalarial Trioxolanes with Diverse Carbamate Side Chains. Acs Medicinal Chemistry Letters. 15: 1764-1770
Suryawanshi RK, Jaishankar P, Correy GJ, et al. (2024) The Mac1 ADP-ribosylhydrolase is a Therapeutic Target for SARS-CoV-2. Biorxiv : the Preprint Server For Biology
Pezacki AT, Gonciarz RL, Okamura T, et al. (2024) A tandem activity-based sensing and labeling strategy reveals antioxidant response element regulation of labile iron pools. Proceedings of the National Academy of Sciences of the United States of America. 121: e2401579121
Gonciarz RL, Jiang H, Tram L, et al. (2023) In vivo bioluminescence imaging of labile iron in xenograft models and liver using FeAL-1, an iron-activatable form of D-luciferin. Cell Chemical Biology
Admasu TD, Kim K, Rae M, et al. (2023) Selective ablation of primary and paracrine senescent cells by targeting iron dyshomeostasis. Cell Reports. 42: 112058
Gonciarz RL, Sakhamuri S, Hooshdaran N, et al. (2023) Elevated labile iron in castration-resistant prostate cancer is targetable with ferrous iron-activatable antiandrogen therapy. European Journal of Medicinal Chemistry. 249: 115110
Jiang H, Muir RK, Gonciarz RL, et al. (2022) Ferrous iron-activatable drug conjugate achieves potent MAPK blockade in KRAS-driven tumors. The Journal of Experimental Medicine. 219
Chen J, Gonciarz RL, Renslo AR. (2021) Correction: Expanded scope of Griesbaum co-ozonolysis for the preparation of structurally diverse sensors of ferrous iron. Rsc Advances. 11: 36625
Chen J, Gonciarz RL, Renslo AR. (2021) Expanded scope of Griesbaum co-ozonolysis for the preparation of structurally diverse sensors of ferrous iron. Rsc Advances. 11: 34338-34342
Gonciarz RL, Renslo AR. (2021) Emerging role of ferrous iron in bacterial growth and host-pathogen interaction: New tools for chemical (micro)biology and antibacterial therapy. Current Opinion in Chemical Biology. 61: 170-178
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