David Donald Scott
Affiliations: | University of Arizona, Tucson, AZ |
Area:
Pharmacology (Biophysics)Google:
"David Scott"Mean distance: (not calculated yet)
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Publications
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Schmidt T, Dabrowska A, Waldron JA, et al. (2023) eIF4A1-dependent mRNAs employ purine-rich 5'UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation. Nucleic Acids Research |
François-Moutal L, Scott DD, Ambrose AJ, et al. (2022) Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology. Scientific Reports. 12: 8140 |
Cai S, Moutal A, Yu J, et al. (2021) Selective targeting of NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents. Science Translational Medicine. 13: eabh1314 |
Francois-Moutal L, Scott DD, Khanna M. (2021) Direct targeting of TDP-43, from small molecules to biologics: the therapeutic landscape. Rsc Chemical Biology. 2: 1158-1166 |
Mollasalehi N, Francois-Moutal L, Scott DD, et al. (2020) An Allosteric Modulator of RNA Binding Targeting the N-Terminal Domain of TDP-43 Yields Neuroprotective Properties. Acs Chemical Biology |
François-Moutal L, Perez-Miller S, Scott DD, et al. (2020) Corrigendum: Structural Insights Into TDP-43 and Effects of Post-translational Modifications. Frontiers in Molecular Neuroscience. 13: 45 |
François-Moutal L, Perez-Miller S, Scott DD, et al. (2019) Structural Insights Into TDP-43 and Effects of Post-translational Modifications. Frontiers in Molecular Neuroscience. 12: 301 |
Zhou Y, Cai S, Moutal A, et al. (2019) The natural flavonoid Naringenin elicits analgesia through inhibition of NaV1.8 voltage-gated sodium channels. Acs Chemical Neuroscience |
Francois-Moutal L, Scott DD, Felemban R, et al. (2019) A small molecule targeting TDP-43's RNA recognition motifs reduces locomotor defects in a Drosophila model of ALS. Acs Chemical Biology |
Scott DD, Francois-Moutal L, Kumirov VK, et al. (2019) H, N and C backbone assignment of apo TDP-43 RNA recognition motifs. Biomolecular Nmr Assignments |