John F. Hunt, Ph.D.

1993 Molecular Biophysics Yale University, New Haven, CT 
 1992-1997 Medical Center U. Texas - Southwestern 
 1997- Biological Sciences Columbia University, New York, NY 
"John Hunt"
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Günter Blobel research assistant 1983-1984 Rockefeller
Donald M. Engelman grad student 1993 Yale
Johann Deisenhofer post-doc 1992-1997 UT Southwestern


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Chi Wang grad student 2003-2011 Columbia
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Li Y, Zhang R, Wang C, et al. (2022) Oligomeric interactions maintain active-site structure in a noncooperative enzyme family. The Embo Journal. e108368
Bahia MS, Khazanov N, Zhou Q, et al. (2021) Stability Prediction for Mutations in the Cytosolic Domains of Cystic Fibrosis Transmembrane Conductance Regulator. Journal of Chemical Information and Modeling
Wang C, Aleksandrov AA, Yang Z, et al. (2018) Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator. The Journal of Biological Chemistry
Yang Z, Wang C, Zhou Q, et al. (2014) Membrane protein stability can be compromised by detergent interactions with the extramembranous soluble domains. Protein Science : a Publication of the Protein Society. 23: 769-89
Chen B, Boël G, Hashem Y, et al. (2014) EttA regulates translation by binding the ribosomal E site and restricting ribosome-tRNA dynamics. Nature Structural & Molecular Biology. 21: 152-9
Uemura Y, Nakagawa N, Wakamatsu T, et al. (2013) Crystal structure of the ligand-binding form of nanoRNase from Bacteroides fragilis, a member of the DHH/DHHA1 phosphoesterase family of proteins. Febs Letters. 587: 2669-74
Hunt JF, Wang C, Ford RC. (2013) Cystic fibrosis transmembrane conductance regulator (ABCC7) structure. Cold Spring Harbor Perspectives in Medicine. 3: a009514
Kim DM, Zheng H, Huang YJ, et al. (2013) ATPase active-site electrostatic interactions control the global conformation of the 100 kDa SecA translocase. Journal of the American Chemical Society. 135: 2999-3010
Pastore C, Topalidou I, Forouhar F, et al. (2012) Crystal structure and RNA binding properties of the RNA recognition motif (RRM) and AlkB domains in human AlkB homolog 8 (ABH8), an enzyme catalyzing tRNA hypermodification. The Journal of Biological Chemistry. 287: 2130-43
Kryshtafovych A, Moult J, Bartual SG, et al. (2011) Target highlights in CASP9: Experimental target structures for the critical assessment of techniques for protein structure prediction. Proteins. 79: 6-20
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