John F. Hunt, Ph.D.
Affiliations: | 1993 | Molecular Biophysics | Yale University, New Haven, CT |
| 1992-1997 | Medical Center | U. Texas - Southwestern | |
| 1997- | Biological Sciences | Columbia University, New York, NY |
Area:
BiophysicsWebsite:
https://www.biology.columbia.edu/people/huntGoogle:
"John Hunt"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Günter Blobel | research assistant | 1983-1984 | Rockefeller |
| Donald M. Engelman | grad student | 1993 | Yale |
| Johann Deisenhofer | post-doc | 1992-1997 | UT Southwestern |
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Publications
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| Li Y, Zhang R, Wang C, et al. (2022) Oligomeric interactions maintain active-site structure in a noncooperative enzyme family. The Embo Journal. e108368 |
| Bahia MS, Khazanov N, Zhou Q, et al. (2021) Stability Prediction for Mutations in the Cytosolic Domains of Cystic Fibrosis Transmembrane Conductance Regulator. Journal of Chemical Information and Modeling |
| Wang C, Aleksandrov AA, Yang Z, et al. (2018) Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator. The Journal of Biological Chemistry |
| Yang Z, Wang C, Zhou Q, et al. (2014) Membrane protein stability can be compromised by detergent interactions with the extramembranous soluble domains. Protein Science : a Publication of the Protein Society. 23: 769-89 |
| Chen B, Boël G, Hashem Y, et al. (2014) EttA regulates translation by binding the ribosomal E site and restricting ribosome-tRNA dynamics. Nature Structural & Molecular Biology. 21: 152-9 |
| Uemura Y, Nakagawa N, Wakamatsu T, et al. (2013) Crystal structure of the ligand-binding form of nanoRNase from Bacteroides fragilis, a member of the DHH/DHHA1 phosphoesterase family of proteins. Febs Letters. 587: 2669-74 |
| Hunt JF, Wang C, Ford RC. (2013) Cystic fibrosis transmembrane conductance regulator (ABCC7) structure. Cold Spring Harbor Perspectives in Medicine. 3: a009514 |
| Kim DM, Zheng H, Huang YJ, et al. (2013) ATPase active-site electrostatic interactions control the global conformation of the 100 kDa SecA translocase. Journal of the American Chemical Society. 135: 2999-3010 |
| Pastore C, Topalidou I, Forouhar F, et al. (2012) Crystal structure and RNA binding properties of the RNA recognition motif (RRM) and AlkB domains in human AlkB homolog 8 (ABH8), an enzyme catalyzing tRNA hypermodification. The Journal of Biological Chemistry. 287: 2130-43 |
| Kryshtafovych A, Moult J, Bartual SG, et al. (2011) Target highlights in CASP9: Experimental target structures for the critical assessment of techniques for protein structure prediction. Proteins. 79: 6-20 |