Barrie Wilkinson

John Innes Centre, UK 
Biosynthesis, natural products, chemical biology
"Barrie Wilkinson"
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Gomez-Escribano JP, Algora Gallardo L, Bozhüyük KAJ, et al. (2021) Genome editing reveals that pSCL4 is required for chromosome linearity in . Microbial Genomics. 7
Bozhüyük KA, Micklefield J, Wilkinson B. (2019) Engineering enzymatic assembly lines to produce new antibiotics. Current Opinion in Microbiology. 51: 88-96
Vikeli E, Widdick DA, Batey SF, et al. (2019) activation and heterologous production of a cryptic lantibiotic from a plant-ant derived species. Applied and Environmental Microbiology
Heine D, Holmes NA, Worsley SF, et al. (2018) Chemical warfare between leafcutter ant symbionts and a co-evolved pathogen. Nature Communications. 9: 2208
Wlodek A, Kendrew SG, Coates NJ, et al. (2017) Diversity oriented biosynthesis via accelerated evolution of modular gene clusters. Nature Communications. 8: 1206
Law BJC, Struck AW, Bennett MR, et al. (2015) Site-specific bioalkylation of rapamycin by the RapM 16-O-methyltransferase. Chemical Science. 6: 2885-2892
Alt S, Wilkinson B. (2015) Biosynthesis of the Novel Macrolide Antibiotic Anthracimycin. Acs Chemical Biology. 10: 2468-79
Medema MH, Kottmann R, Yilmaz P, et al. (2015) Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology. 11: 625-31
Schäfer M, Le TB, Hearnshaw SJ, et al. (2015) SimC7 Is a Novel NAD(P)H-Dependent Ketoreductase Essential for the Antibiotic Activity of the DNA Gyrase Inhibitor Simocyclinone. Journal of Molecular Biology. 427: 2192-204
Wu MC, Law B, Wilkinson B, et al. (2012) Bioengineering natural product biosynthetic pathways for therapeutic applications. Current Opinion in Biotechnology. 23: 931-40
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