Simon J Hedley

Affiliations: 
1995-2003 Chemistry University of Sheffield, Sheffield, England, United Kingdom 
 2003-2006 Chemistry State University of New York, Buffalo, Buffalo, NY, United States 
 2006-2018 Drug Substance Synthetic Technologies Amgen Inc., Thousand Oaks, CA, United States 
 2020-2021 Drug Substance Arcinova 
 2021- Drug Substance PR&D Quotient Sciences 
Area:
Process Chemistry, Organic Synthesis, Catalysis, Crystallisation, Biocatalysis
Google:
"Simon Hedley"
Mean distance: (not calculated yet)
 
BETA: Related publications

Publications

You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect.

Wurz RP, Pettus LH, Ashton K, et al. (2015) Oxopyrido[2,3-d]pyrimidines as Covalent L858R/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors. Acs Medicinal Chemistry Letters. 6: 987-92
Davies HM, Hedley SJ. (2007) Intermolecular reactions of electron-rich heterocycles with copper and rhodium carbenoids. Chemical Society Reviews. 36: 1109-19
Murthy V, Davies HM, Hedley SJ, et al. (2007) Irreversible binding of a novel phenylisothiocyanate tropane analog to monoamine transporters in rat brain. Biochemical Pharmacology. 74: 336-44
Hedley SJ, Ventura DL, Dominiak PM, et al. (2006) Investigation into factors influencing stereoselectivity in the reactions of heterocycles with donor-acceptor-substituted rhodium carbenoids. The Journal of Organic Chemistry. 71: 5349-56
Davies HM, Hedley SJ, Bohall BR. (2005) Asymmetric intermolecular C-H functionalization of benzyl silyl ethers mediated by chiral auxiliary-based aryldiazoacetates and chiral dirhodium catalysts. The Journal of Organic Chemistry. 70: 10737-42
Hedley SJ, Moran WJ, Price DA, et al. (2003) Development of a [3+3] cycloaddition strategy toward functionalized piperidines. The Journal of Organic Chemistry. 68: 4286-92
Hedley SJ, Moran WJ, Prenzel AGHP, et al. (2001) Synthesis of Functionalised Piperidines Through a [3 + 3] Cycloaddition Strategy Synlett. 1596-1598
See more...