Wenzhen Fu

Affiliations: 
 
Area:
biocatalysis, protein engineering, directed evolution, asymmetric catalysis
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"Wenzhen Fu"
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Fu W, Neris NM, Fu Y, et al. (2023) Enzyme-controlled stereoselective radical cyclization to arenes enabled by metalloredox biocatalysis. Nature Catalysis. 6: 628-636
Chen Y, Zhai N, Zhu Y, et al. (2023) Azetidine ring, salicylic acid, and salicylic acid bioisosteres as determinants of the binding characteristics of novel potent compounds to Stat3. Bioorganic & Medicinal Chemistry Letters. 129565
Chen H, Fu W, Yang Y. (2023) P450-catalyzed atom transfer radical cyclization. Methods in Enzymology. 693: 31-49
Fu W, Yang Y. (2022) Undirected biocatalytic amination of unactivated C( )-H bonds. Chem Catalysis. 2: 3287-3289
Fu Y, Chen H, Fu W, et al. (2022) Engineered P450 Atom-Transfer Radical Cyclases are Bifunctional Biocatalysts: Reaction Mechanism and Origin of Enantioselectivity. Journal of the American Chemical Society
Yue P, Zhu Y, Brotherton-Pleiss C, et al. (2022) Novel potent azetidine-based compounds irreversibly inhibit Stat3 activation and induce antitumor response against human breast tumor growth in vivo. Cancer Letters. 534: 215613
Brotherton-Pleiss C, Yue P, Zhu Y, et al. (2020) Discovery of Novel Azetidine Amides as Potent Small-Molecule STAT3 Inhibitors. Journal of Medicinal Chemistry
Fu W, Nie M, Wang A, et al. (2015) Highly enantioselective nickel-catalyzed intramolecular reductive cyclization of alkynones. Angewandte Chemie (International Ed. in English). 54: 2520-4
Xu G, Fu W, Liu G, et al. (2014) Efficient syntheses of korupensamines A, B and michellamine B by asymmetric Suzuki-Miyaura coupling reactions. Journal of the American Chemical Society. 136: 570-3
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