James Keane Bashkin

Affiliations: 
University of Missouri-St. Louis, St. Louis, MO, United States 
Area:
Chemistry, polyamides, antivirals, gene chemistry, bioorganic, organic, biochemistry, biophysics
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"James Bashkin"
Mean distance: 7.32
 
SNBCP

Parents

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Malcolm L.H. Green grad student 1977-1982 Oxford
 (D.Phil.)
Richard Hadley Holm post-doc 1983-1985 Harvard
 (NIH postdoctoral fellow)
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Publications

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Niederschulte J, Song Y, Park AH, et al. (2021) DNA binding site kinetics of a large antiviral polyamide. Biochimie
Liu B, Bashkin JK, Poon GMK, et al. (2019) Modulating DNA by polyamides to regulate transcription factor PU.1-DNA binding interactions. Biochimie
Song Y, Niederschulte J, Bales KN, et al. (2019) DNA Binding Thermodynamics and Site Stoichiometry as a Function of Polyamide Size. Biochimie
Song Y, Niederschulte J, Bales KN, et al. (2018) Thermodynamics and Site Stoichiometry of DNA Binding by a Large Antiviral Hairpin Polyamide. Biochimie
Liu B, Wang S, Aston K, et al. (2017) β-Alanine and N-terminal cationic substituents affect polyamide-DNA binding. Organic & Biomolecular Chemistry
Castaneda CH, Scuderi MJ, Edwards TG, et al. (2016) Improved Antiviral Activity of a Polyamide Against High-Risk Human Papillomavirus Via N-Terminal Guanidinium Substitution. Medchemcomm. 7: 2076-2082
Vasilieva E, Niederschulte J, Song Y, et al. (2016) Interactions of Two Large Antiviral Polyamides with the Long Control Region of HPV16. Biochimie
He G, Bashkin JK. (2015) What is the antiviral potential of pyrrole-imidazole polyamides? Future Medicinal Chemistry. 7: 1953-5
Vasilieva E, Song Y, Koeller KJ, et al. (2015) 134 Large antiviral polyamide-DNA interactions. Journal of Biomolecular Structure & Dynamics. 33: 86-7
He G, Tolic A, Bashkin JK, et al. (2015) Heterogeneous dynamics in DNA site discrimination by the structurally homologous DNA-binding domains of ETS-family transcription factors. Nucleic Acids Research. 43: 4322-31
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