Giuseppe Melacini, PhD
Affiliations: | Chemistry and Chemical Biology | McMaster University, Hamilton, ON, Canada |
Area:
NMR Spectroscopy, Protein Structure, DynamicsWebsite:
http://www.chemistry.mcmaster.ca/melacini/Google:
"Giuseppe Melacini"Mean distance: 8.15 | S | N | B | C | P |
Parents
Sign in to add mentor| Rolf Boelens | grad student | ||
| Murray Goodman | grad student | UCSD | |
| Robert Kaptein | post-doc | Utrecht |
Children
Sign in to add trainee| Rahul Das | grad student | McMaster University | |
| Naeimeh Jafari | grad student | ||
| Julijana Milojevic | grad student | McMaster University | |
| Rajeevan Selvaratnam | grad student | 2007-2013 | McMaster University |
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Publications
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| Mohamed H, Baryar U, Bashiri A, et al. (2022) Identification of Core Allosteric Sites through Temperature- and Nucleus-Invariant Chemical Shift Covariance. Biophysical Journal |
| McNicholl ET, Das R, SilDas S, et al. (2021) Backbone resonance assignment of the cAMP-binding domains of the protein kinase A regulatory subunit Iα. Biomolecular Nmr Assignments |
| Jafari N, Del Rio J, Akimoto M, et al. (2021) Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Byun JA, VanSchouwen B, Akimoto M, et al. (2020) Allosteric inhibition explained through conformational ensembles sampling distinct "mixed" states. Computational and Structural Biotechnology Journal. 18: 3803-3818 |
| Shao H, Boulton S, Olivieri C, et al. (2020) CHESPA/CHESCA-SPARKY: automated NMR data analysis plugins for SPARKY to map protein allostery. Bioinformatics (Oxford, England) |
| Boulton S, Van K, VanSchouwen B, et al. (2020) Allosteric Mechanisms of Nonadditive Substituent Contributions to Protein-Ligand Binding. Biophysical Journal |
| Martinez Pomier K, Ahmed R, Melacini G. (2020) Catechins as Tools to Understand the Molecular Basis of Neurodegeneration. Molecules (Basel, Switzerland). 25 |
| García-Viñuales S, Ahmed R, Sciacca MFM, et al. (2020) Trehalose conjugates of silybin as prodrugs for targeting toxic Aβ aggregates. Acs Chemical Neuroscience |
| Byun JA, Akimoto M, VanSchouwen B, et al. (2020) Allosteric pluripotency as revealed by protein kinase A. Science Advances. 6: eabb1250 |
| Akimoto M, Yu T, Moleschi K, et al. (2020) An NMR based phosphodiesterase assay. Chemical Communications (Cambridge, England) |