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Grace Brannigan, Ph.D.

Affiliations: 
Physics Rutgers University, Camden 
Area:
Computational Biophysics, Membrane Protein Pharmacology
Website:
Branniganlab.wordpress
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"Grace Brannigan"
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SNBCP

Parents

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Frank L. Brown grad student 2006 UC Santa Barbara
Philip Pincus grad student 2000-2006 (Physics Tree)
Michael L. Klein post-doc 2006-2011 Penn

Collaborators

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Jérôme Hénin collaborator
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Publications

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Sandberg JW, Santiago-McRae E, Ennis J, et al. (2024) The density-threshold affinity: Calculating lipid binding affinities from unbiased coarse-grained molecular dynamics simulations. Methods in Enzymology. 701: 47-82
Pitman C, Santiago-McRae E, Lohia R, et al. (2024) The blobulator: a webtool for identification and visual exploration of hydrophobic modularity in protein sequences. Biorxiv : the Preprint Server For Biology
Joseph TT, Bu W, Haji-Ghassemi O, et al. (2024) Propofol directly binds and inhibits skeletal muscle ryanodine receptor 1 (RyR1). Biorxiv : the Preprint Server For Biology
Dalal V, Arcario MJ, Petroff JT, et al. (2024) Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel. Nature Communications. 15: 25
Petroff JT, Dietzen NM, Santiago-McRae E, et al. (2022) Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation. Nature Communications. 13: 7017
Lohia R, Hansen MEB, Brannigan G. (2022) Contiguously hydrophobic sequences are functionally significant throughout the human exome. Proceedings of the National Academy of Sciences of the United States of America. 119: e2116267119
Dietzen NM, Arcario MJ, Chen LJ, et al. (2022) Polyunsaturated fatty acids inhibit a pentameric ligand-gated ion channel through one of two binding sites. Elife. 11
Sharp L, Brannigan G. (2021) Spontaneous lipid binding to the nicotinic acetylcholine receptor in a native membrane. The Journal of Chemical Physics. 154: 185102
Joseph TT, Bu W, Lin W, et al. (2021) Ketamine Metabolite (2,6)-Hydroxynorketamine Interacts with μ and κ Opioid Receptors. Acs Chemical Neuroscience
Lohia R, Bassi K, Hansen M, et al. (2020) Disease Associated Mutations in Intrinsically Disordered Proteins Show Evidence of Enrichment in Hydrophobic Blobs Biophysical Journal. 118
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