Didier Rognan

CNRS, Paris, Île-de-France, France 
"Didier Rognan"
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Hoch L, Faure H, Roudaut H, et al. (2015) MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1817-29
Hounsou C, Margathe JF, Oueslati N, et al. (2015) Time-resolved FRET binding assay to investigate hetero-oligomer binding properties: proof of concept with dopamine D1/D3 heterodimer. Acs Chemical Biology. 10: 466-74
Cazorla M, Prémont J, Mann A, et al. (2011) Identification of a low-molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice. The Journal of Clinical Investigation. 121: 1846-57
Kellenberger E, Springael JY, Parmentier M, et al. (2007) Identification of nonpeptide CCR5 receptor agonists by structure-based virtual screening. Journal of Medicinal Chemistry. 50: 1294-303
Krier M, Bret G, Rognan D. (2006) Assessing the scaffold diversity of screening libraries. Journal of Chemical Information and Modeling. 46: 512-24
Krier M, Araújo-Júnior JX, Schmitt M, et al. (2005) Design of small-sized libraries by combinatorial assembly of linkers and functional groups to a given scaffold: application to the structure-based optimization of a phosphodiesterase 4 inhibitor. Journal of Medicinal Chemistry. 48: 3816-22
Tahtaoui C, Balestre MN, Klotz P, et al. (2003) Identification of the binding sites of the SR49059 nonpeptide antagonist into the V1a vasopressin receptor using sulfydryl-reactive ligands and cysteine mutants as chemical sensors. The Journal of Biological Chemistry. 278: 40010-9
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