Wezley Colyn Griffin

St Jude Children's Research Hospital, New York, NY, United States 
Biochemistry, molecular biology, biophysics
"Wezley Griffin"
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Griffin WC, McKinzey DR, Klinzing KN, et al. (2022) A multi-functional role for the MCM8/9 helicase complex in maintaining fork integrity during replication stress. Nature Communications. 13: 5090
McKinzey DR, Gomathinayagam S, Griffin WC, et al. (2021) Motifs of the C-terminal domain of MCM9 direct localization to sites of mitomycin-C damage for RAD51 recruitment. The Journal of Biological Chemistry. 100355
Perera HM, Behrmann MS, Hoang JM, et al. (2019) Contacts and context that regulate DNA helicase unwinding and replisome progression. The Enzymes. 45: 183-223
Griffin WC, Trakselis MA. (2019) The MCM8/9 complex: A recent recruit to the roster of helicases involved in genome maintenance. Dna Repair. 76: 1-10
Griffin WC, Gao J, Byrd AK, et al. (2017) A Biochemical and Biophysical Model of G-quadruplex DNA Recognition by Positive Coactivator of Transcription 4. The Journal of Biological Chemistry
Lopez CR, Singh S, Hambarde S, et al. (2017) Yeast Sub1 and human PC4 are G-quadruplex binding proteins that suppress genome instability at co-transcriptionally formed G4 DNA. Nucleic Acids Research
Byrd AK, Zybailov BL, Maddukuri L, et al. (2016) Evidence that G-quadruplex DNA Accumulates in the Cytoplasm and Participates in Stress Granule Assembly in Response to Oxidative Stress. The Journal of Biological Chemistry
Gao J, Zybailov BL, Byrd AK, et al. (2015) Yeast transcription co-activator Sub1 and its human homolog PC4 preferentially bind to G-quadruplex DNA. Chemical Communications (Cambridge, England). 51: 7242-4
Maddukuri L, Ketkar A, Eddy S, et al. (2012) Enhancement of human DNA polymerase η activity and fidelity is dependent upon a bipartite interaction with the Werner syndrome protein. The Journal of Biological Chemistry. 287: 42312-23
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