Ian B. Seiple, Ph.D.

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Website:
http://www.seiplegroup.com
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Parents

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Dirk Trauner research assistant 2004-2006 UC Berkeley
Phil S. Baran grad student 2006-2011 Scripps Institute
Andrew G. Myers post-doc 2011-2015 Harvard
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Publications

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Cai L, Seiple IB, Li Q. (2021) Modular Chemical Synthesis of Streptogramin and Lankacidin Antibiotics. Accounts of Chemical Research
Boyce JH, Dang B, Ary B, et al. (2020) Platform to Discover Protease-Activated Antibiotics and Application to Siderophore-Antibiotic Conjugates. Journal of the American Chemical Society
Sundaram A, Chen C, Isik Reed N, et al. (2020) Dual antagonists of α5β1/ αvβ1 integrin for airway hyperresponsiveness. Bioorganic & Medicinal Chemistry Letters. 127578
Li Q, Seiple IB. (2019) A concise route to virginiamycin M2. Tetrahedron. 75: 3309-3318
Yao Y, Cai L, Seiple IB. (2018) Synthesis, Structural Reassignment, and Antibacterial Evaluation of 2,18-Seco-Lankacidinol B. Angewandte Chemie (International Ed. in English)
Li Q, Seiple IB. (2017) Modular, Scalable Synthesis of Group A Streptogramin Antibiotics. Journal of the American Chemical Society
Seiple IB, Zhang Z, Jakubec P, et al. (2016) A platform for the discovery of new macrolide antibiotics. Nature. 533: 338-45
Seiple IB, Hog DT, Myers AG. (2015) Practical Protocols for the Preparation of Highly Enantioenriched Silyl Ethers of (R)-3-Hydroxypentan-2-one, Building Blocks for the Synthesis of Macrolide Antibiotics Synlett
Wright PM, Seiple IB, Myers AG. (2014) The evolving role of chemical synthesis in antibacterial drug discovery. Angewandte Chemie (International Ed. in English). 53: 8840-69
Seiple IB, Mercer JA, Sussman RJ, et al. (2014) Stereocontrolled synthesis of syn-β-Hydroxy-α-amino acids by direct aldolization of pseudoephenamine glycinamide. Angewandte Chemie (International Ed. in English). 53: 4642-7
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