Ian B. Seiple, Ph.D.
Affiliations: | University of California, San Francisco, San Francisco, CA |
Website:
http://www.seiplegroup.comGoogle:
"Ian Seiple"Mean distance: 8.01 | S | N | B | C | P |
Parents
Sign in to add mentor| Dirk Trauner | research assistant | 2004-2006 | UC Berkeley |
| Phil S. Baran | grad student | 2006-2011 | Scripps Institute |
| Andrew G. Myers | post-doc | 2011-2015 | Harvard |
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Publications
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| Cai L, Seiple IB, Li Q. (2021) Modular Chemical Synthesis of Streptogramin and Lankacidin Antibiotics. Accounts of Chemical Research |
| Boyce JH, Dang B, Ary B, et al. (2020) Platform to Discover Protease-Activated Antibiotics and Application to Siderophore-Antibiotic Conjugates. Journal of the American Chemical Society |
| Sundaram A, Chen C, Isik Reed N, et al. (2020) Dual antagonists of α5β1/ αvβ1 integrin for airway hyperresponsiveness. Bioorganic & Medicinal Chemistry Letters. 127578 |
| Li Q, Seiple IB. (2019) A concise route to virginiamycin M2. Tetrahedron. 75: 3309-3318 |
| Yao Y, Cai L, Seiple IB. (2018) Synthesis, Structural Reassignment, and Antibacterial Evaluation of 2,18-Seco-Lankacidinol B. Angewandte Chemie (International Ed. in English) |
| Li Q, Seiple IB. (2017) Modular, Scalable Synthesis of Group A Streptogramin Antibiotics. Journal of the American Chemical Society |
| Seiple IB, Zhang Z, Jakubec P, et al. (2016) A platform for the discovery of new macrolide antibiotics. Nature. 533: 338-45 |
| Seiple IB, Hog DT, Myers AG. (2015) Practical Protocols for the Preparation of Highly Enantioenriched Silyl Ethers of (R)-3-Hydroxypentan-2-one, Building Blocks for the Synthesis of Macrolide Antibiotics Synlett |
| Wright PM, Seiple IB, Myers AG. (2014) The evolving role of chemical synthesis in antibacterial drug discovery. Angewandte Chemie (International Ed. in English). 53: 8840-69 |
| Seiple IB, Mercer JA, Sussman RJ, et al. (2014) Stereocontrolled synthesis of syn-β-Hydroxy-α-amino acids by direct aldolization of pseudoephenamine glycinamide. Angewandte Chemie (International Ed. in English). 53: 4642-7 |