Jeremy R. Lohman, Ph.D.

Affiliations: 
Biochemistry Purdue University, West Lafayette, IN, United States 
Area:
Natural Product Biosynthesis
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"Jeremy Lohman"
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Parents

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Lisa M. Gloss grad student 2001-2003 WSU
S James Remington grad student 2007 University of Oregon
 (Two-state conformational behavior in protein active centers.)
S James Remington grad student 2007 University of Oregon
 (Two-state conformational behavior in protein active centers.)
Ben Shen post-doc Scripps Institute
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Publications

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Lohman JR, Shen B. (2020) The LnmK Bifunctional Acyltransferase/Decarboxylase Specifying (2)-Methylmalonyl-CoA and Employing Substrate-Assisted Catalysis for Polyketide Biosynthesis. Biochemistry
Kwong T, Ma M, Pan G, et al. (2018) P450-Catalyzed Tailoring Steps in Leinamycin Biosynthesis Featuring Regio- and Stereoselective Hydroxylations and Substrate Promiscuities. Biochemistry
Chang CY, Lohman JR, Huang T, et al. (2018) Structural Insights into the Free-standing Condensation Enzyme SgcC5 Catalyzing Ester Bond Formation in the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027. Biochemistry
Guo X, Crnovcic I, Chang CY, et al. (2018) PokMT1 from the polyketomycin biosynthetic machinery of Streptomyces diastatochromogenes Tü6028 belongs to the emerging family of C-methyltransferases that act on CoA-activated aromatic substrates. Biochemistry
Annaval T, Rudolf JD, Chang CY, et al. (2017) Crystal Structure of Thioesterase SgcE10 Supporting Common Polyene Intermediates in 9- and 10-Membered Enediyne Core Biosynthesis. Acs Omega. 2: 5159-5169
Yan X, Ge H, Huang T, et al. (2016) Strain Prioritization and Genome Mining for Enediyne Natural Products. Mbio. 7
Chang CY, Lohman JR, Cao H, et al. (2016) Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase that Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate in Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus. Biochemistry
Huang T, Chang CY, Lohman JR, et al. (2016) Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027. The Journal of Antibiotics
Rudolf JD, Bigelow L, Chang C, et al. (2015) Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892. Biochemistry
Lohman JR, Ma M, Osipiuk J, et al. (2015) Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases. Proceedings of the National Academy of Sciences of the United States of America
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