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Alfred G. Gilman

Pharmacology University of Texas Southwestern Medical Center, Dallas, TX, United States 
"Alfred Goodman Gilman"

(1941 - 2015)
DOI: 10.1126/science.aaf2848
The Nobel Prize in Physiology or Medicine 1994 was awarded jointly to Alfred G. Gilman and Martin Rodbell for their discovery of G-proteins and the role of these proteins in signal transduction in cells

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Melvin V. Simpson research assistant 1962 Yale
Allan H. Conney research assistant 1962-1962 Burroughs Wellcome Co.
 (Summer project.)
Theodore W. Rall grad student 1969 Case Western
 (Studies on the role of adenosine 3', 5' -phosphate in mediating the actions of thyroid-stimulating hormone)
Marshall Nirenberg post-doc 1969-1971 NIH
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Gilman AG. (2012) Silver spoons and other personal reflections. Annual Review of Pharmacology and Toxicology. 52: 1-19
Gilman A. (2009) Newsmaker interview. Texas transplant Alfred Gilman guides $3 billion cancer project. Interview by Jocelyn Kaiser. Science (New York, N.Y.). 324: 868
Hardman JG, Gilman AG. (2007) David L. Garbers (1944–2006) Annual Review of Physiology. 69
Krumins AM, Gilman AG. (2006) Targeted knockdown of G protein subunits selectively prevents receptor-mediated modulation of effectors and reveals complex changes in non-targeted signaling proteins. The Journal of Biological Chemistry. 281: 10250-62
Gibson SK, Gilman AG. (2006) Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors. Proceedings of the National Academy of Sciences of the United States of America. 103: 212-7
Tall GG, Gilman AG. (2005) Resistance to inhibitors of cholinesterase 8A catalyzes release of Galphai-GTP and nuclear mitotic apparatus protein (NuMA) from NuMA/LGN/Galphai-GDP complexes. Proceedings of the National Academy of Sciences of the United States of America. 102: 16584-9
Tall GG, Gilman AG. (2004) Purification and functional analysis of Ric-8A: a guanine nucleotide exchange factor for G-protein alpha subunits. Methods in Enzymology. 390: 377-88
Hatley ME, Lockless SW, Gibson SK, et al. (2003) Allosteric determinants in guanine nucleotide-binding proteins. Proceedings of the National Academy of Sciences of the United States of America. 100: 14445-50
Chen Z, Raman M, Chen L, et al. (2003) TAO (thousand-and-one amino acid) protein kinases mediate signaling from carbachol to p38 mitogen-activated protein kinase and ternary complex factors. The Journal of Biological Chemistry. 278: 22278-83
Tall GG, Krumins AM, Gilman AG. (2003) Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor. The Journal of Biological Chemistry. 278: 8356-62
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