Craig W. Lindsley, Ph.D.

Affiliations: 
2006- Pharmacology Vanderbilt University, Nashville, TN 
Website:
http://www.mc.vanderbilt.edu/labs/lindsley/lindsleycw.html
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Emily Jeanne Lilla research assistant 2017- Vanderbilt
Pedro Manuel Garcia-Barrantes grad student Vanderbilt
Evan P. Lebois grad student Vanderbilt (Neurotree)
Kellie D. Nance grad student Vanderbilt
Jeanette L Bertron grad student 2016- Vanderbilt
Richard Nathan Daniels grad student 2010 Vanderbilt
J. Phillip Kennedy grad student 2010 Vanderbilt
Olugbeminiyi Fadeyi grad student 2011 Vanderbilt
Leslie N. Aldrich grad student 2012 Vanderbilt
Sydney Lear Stoops grad student 2012 Vanderbilt
Michael L. Schulte grad student 2009-2013 Vanderbilt
Robert Raymond Lavieri grad student 2014 Vanderbilt
Timothy J. Senter grad student 2010-2015 Vanderbilt
Cody J. Wenthur grad student 2011-2015 Vanderbilt
Caitlin N Kent grad student 2019-2020
Kayla J. Temple post-doc 2014- Vanderbilt
Aaron T Garrison post-doc 2018-2019 Vanderbilt
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Publications

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Garrison AT, Orsi DL, Capstick RA, et al. (2022) Development of : A Potent, Highly Selective, and Systemically Active Orthosteric Antagonist of the M Muscarinic Acetylcholine Receptor for the Treatment of Opioid Use Disorder. Journal of Medicinal Chemistry
McClenahan SJ, Kent C, Kharade S, et al. (2022) . Molecular Pharmacology
Bertron JL, Duvernay MT, Mitchell SG, et al. (2021) Discovery and Optimization of a Novel Series of Competitive and Central Nervous System-Penetrant Protease-Activated Receptor 4 (PAR4) Inhibitors. Acs Chemical Neuroscience
Long MF, Capstick RA, Spearing PK, et al. (2021) Development of structurally distinct tricyclic M positive allosteric modulator (PAM) chemotypes - Part 2. Bioorganic & Medicinal Chemistry Letters. 128416
Yamada Y, Gilliland K, Xiang Z, et al. (2021) Positive allosteric modulators (PAMs) of the group II metabotropic glutamate receptors: Design, synthesis, and evaluation as ex-vivo tool compounds. Bioorganic & Medicinal Chemistry Letters. 128342
Kent CN, Fulton MG, Stillwell KJ, et al. (2021) Discovery and optimization of a novel CNS penetrant series of mGlu PAMs based on a 1,4-thiazepane core with in vivo efficacy in a preclinical Parkinsonian model. Bioorganic & Medicinal Chemistry Letters. 127838
Reed CW, Kalbfleisch JJ, Wong MJ, et al. (2020) Discovery of VU6027459: A First-in-Class Selective and CNS Penetrant mGlu Positive Allosteric Modulator Tool Compound. Acs Medicinal Chemistry Letters. 11: 1773-1779
Kalbfleisch JJ, Reed CW, Park C, et al. (2020) Synthesis and SAR of a series of mGlu NAMs based on an ethyl-8-methoxy-4-(4-phenylpiperazin-1-yl)quinoline carboxylate core. Bioorganic & Medicinal Chemistry Letters. 127529
Kent CN, Park C, Lindsley CW. (2020) Classics in Chemical Neuroscience: Baclofen. Acs Chemical Neuroscience
Fulton MG, Loch MT, Rodriguez AL, et al. (2020) Synthesis and pharmacological evaluation of bivalent tethered ligands to target the mGlu heterodimeric receptor results in a compound with mGlu homodimer selectivity. Bioorganic & Medicinal Chemistry Letters. 127212
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