Rosalía Agusti

Affiliations: 
Universidad de Buenos Aires - CONICET 
Area:
organic chemistry, glycobiology
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"Rosalía Agusti"
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Publications

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Morrone-Pozzuto P, Uhrig ML, Agusti R. (2022) Synthesis of Oligosaccharides Containing the -Gal(α1 → 3)Gal Unit, Glycomimetic of the Epitope Recognized by Lytic Antibodies. The Journal of Organic Chemistry
de Lederkremer RM, Giorgi ME, Agusti R. (2021) -Sialylation: a strategy used to incorporate sialic acid into oligosaccharides. Rsc Chemical Biology. 3: 121-139
Vázquez-Jiménez LK, Paz-González AD, Juárez-Saldivar A, et al. (2020) Structure-Based Virtual Screening of New Benzoic Acid Derivatives as Trypanosoma cruzi Trans-sialidase Inhibitors. Medicinal Chemistry (Shariqah (United Arab Emirates))
Agusti R, Gallo-Rodriguez C, de Lederkremer RM. (2019) Trypanosoma cruzi trans-sialidase. A tool for the synthesis of sialylated oligosaccharides. Carbohydrate Research. 479: 48-58
Morrone-Pozzuto P, Uhrig ML, Agusti R. (2019) Trypanosoma cruzi trans-sialidase alternative substrates: Study of the effect of substitution in C-6 in benzyl β-lactoside. Carbohydrate Research. 478: 33-45
Kashif M, Chacón-Vargas KF, López-Cedillo JC, et al. (2018) Synthesis, molecular docking and biological evaluation of novel phthaloyl derivatives of 3-amino-3-aryl propionic acids as inhibitors of Trypanosoma cruzi trans-sialidase. European Journal of Medicinal Chemistry. 156: 252-268
Giorgi ME, Lopez R, Agusti R, et al. (2017) Synthesis of a model trisaccharide for studying the interplay between the anti α-Gal antibody and the trans-sialidase reactions in Trypanosoma cruzi. Carbohydrate Research. 450: 30-37
Lara-Ramirez EE, López-Cedillo JC, Nogueda-Torres B, et al. (2017) An in vitro and in vivo evaluation of new potential trans-sialidase inhibitors of Trypanosoma cruzi predicted by a computational drug repositioning method. European Journal of Medicinal Chemistry. 132: 249-261
Agustí R, Cano ME, Cagnoni AJ, et al. (2016) Multivalent sialylation of β-thio-glycoclusters by Trypanosoma cruzi trans sialidase and analysis by high performance anion exchange chromatography. Glycoconjugate Journal. 33: 809-18
Agustí R, Giorgi ME, Mendoza VM, et al. (2015) Synthesis of the O-linked hexasaccharide containing β-D-Galp-(1→2)-D-Galf in Trypanosoma cruzi mucins. Differences on sialylation by trans-sialidase of the two constituent hexasaccharides. Bioorganic & Medicinal Chemistry. 23: 1213-22
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