James Turkson
Affiliations: | University of Hawaii Cancer Center |
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Sign in to add traineeWenzhen Fu | grad student | 2018-2020 | University of Hawaii Cancer Center |
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Publications
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Chen Y, Zhai N, Zhu Y, et al. (2023) Azetidine ring, salicylic acid, and salicylic acid bioisosteres as determinants of the binding characteristics of novel potent compounds to Stat3. Bioorganic & Medicinal Chemistry Letters. 129565 |
Zhu Y, Yue P, Dickinson CF, et al. (2022) Natural product preferentially targets redox and metabolic adaptations and aberrantly active STAT3 to inhibit breast tumor growth in vivo. Cell Death & Disease. 13: 1022 |
Yue P, Zhu Y, Brotherton-Pleiss C, et al. (2022) Novel potent azetidine-based compounds irreversibly inhibit Stat3 activation and induce antitumor response against human breast tumor growth in vivo. Cancer Letters. 534: 215613 |
Wang Y, Yang C, Sims MM, et al. (2022) SS-4 is a highly selective small molecule inhibitor of STAT3 tyrosine phosphorylation that potently inhibits GBM tumorigenesis in vitro and in vivo. Cancer Letters. 533: 215614 |
Brotherton-Pleiss C, Yue P, Zhu Y, et al. (2020) Discovery of Novel Azetidine Amides as Potent Small-Molecule STAT3 Inhibitors. Journal of Medicinal Chemistry |
Conway ME, McDaniel JM, Graham JM, et al. (2020) STAT3 and GR cooperate to drive gene expression and growth of basal-like triple-negative breast cancer. Cancer Research |
Dambal S, Alfaqih M, Sanders S, et al. (2020) 27-hydroxycholesterol impairs plasma membrane lipid raft signaling as evidenced by inhibition of IL6-JAK-STAT3 signaling in prostate cancer cells. Molecular Cancer Research : McR |
Neupane RP, Parrish SM, Neupane JB, et al. (2019) Cytotoxic Sesquiterpenoid Quinones and Quinols, and an 11-Membered Heterocycle, Kauamide, from the Hawaiian Marine Sponge . Marine Drugs. 17 |
Li C, Sarotti AM, Wu X, et al. (2019) An Unusual Benzoisoquinoline-9-one Derivative and Other Related Compounds with Antiproliferative Activity from Hawaiian Endophytic Fungus sp. FT431. Molecules (Basel, Switzerland). 24 |
Lopez-Tapia F, Brotherton-Pleiss C, Yue P, et al. (2018) Linker Variation and Structure-Activity Relationship Analyses of Carboxylic Acid-based Small Molecule STAT3 Inhibitors. Acs Medicinal Chemistry Letters. 9: 250-255 |