Christian Ducho

Affiliations: 
Saarland University, Saarbrücken, Saarland, Germany 
Area:
Medicinal chemistry, bioorganic chemistry, chemical biology
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"Christian Ducho"
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Publications

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Cui Z, Nguyen H, Bhardwaj M, et al. (2021) Enzymatic C-H Functionalization of l-Arg and l-Leu in Nonribosomally Derived Peptidyl Natural Products: A Tale of Two Oxidoreductases. Journal of the American Chemical Society. 143: 19425-19437
Cui Z, Overbay J, Wang X, et al. (2020) Pyridoxal-5'-phosphate-dependent alkyl transfer in nucleoside antibiotic biosynthesis. Nature Chemical Biology
Heib A, Niro G, Weck SC, et al. (2019) Muraymycin Nucleoside Antibiotics: Structure-Activity Relationship for Variations in the Nucleoside Unit. Molecules (Basel, Switzerland). 25
Cui Z, Liu X, Overbay J, et al. (2018) Enzymatic Synthesis of the Ribosylated Glycyl-Uridine Disaccharide Core of Peptidyl Nucleoside Antibiotics. The Journal of Organic Chemistry
Cai W, Goswami A, Yang Z, et al. (2015) The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE. The Journal of Biological Chemistry. 290: 13710-24
Hamed RB, Gomez-Castellanos JR, Henry L, et al. (2013) The enzymes of β-lactam biosynthesis. Natural Product Reports. 30: 21-107
Barnard-Britson S, Chi X, Nonaka K, et al. (2012) Amalgamation of nucleosides and amino acids in antibiotic biosynthesis: discovery of an L-threonine:uridine-5'-aldehyde transaldolase. Journal of the American Chemical Society. 134: 18514-7
Hamed RB, Henry L, Gomez-Castellanos JR, et al. (2012) Crotonase catalysis enables flexible production of functionalized prolines and carbapenams. Journal of the American Chemical Society. 134: 471-9
Spork AP, Wiegmann D, Granitzka M, et al. (2011) Stereoselective synthesis of uridine-derived nucleosyl amino acids. The Journal of Organic Chemistry. 76: 10083-98
Hamed RB, Gomez-Castellanos JR, Thalhammer A, et al. (2011) Stereoselective C-C bond formation catalysed by engineered carboxymethylproline synthases. Nature Chemistry. 3: 365-71
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