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Chambers Connor Hughes

Affiliations: 
2004 University of California, Berkeley, Berkeley, CA, United States 
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"Chambers Hughes"
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Dirk Trauner grad student 2004 UC Berkeley
 (Natural product total synthesis: (-)-frondosin B, (-)-amathaspiramide F, guanacastepene A, and rhazinilam and the synthesis and reactivity of novel boron -ammonia complexes.)

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Publications

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Seiler GS, Hughes CC. (2019) Progress toward the Total Synthesis of Lymphostins: Preparation of a Functionalized Tetrahydropyrrolo[4,3,2- de]quinoline and Unusual Oxidative Dimerization. The Journal of Organic Chemistry
Castro-Falcón G, Mill Aacute N Agui Ntilde Aga N, Roullier C, et al. (2018) Nitrosopyridine probe to detect polyketide natural products with conjugated alkenes: Discovery of novodaryamide and nocarditriene. Acs Chemical Biology
Reimer D, Hughes CC. (2017) Thiol-Based Probe for Electrophilic Natural Products Reveals That Most of the Ammosamides Are Artifacts. Journal of Natural Products
Alvarez-Mico X, Jensen PR, Fenical W, et al. (2013) Chlorizidine, a cytotoxic 5H-pyrrolo[2,1-a]isoindol-5-one-containing alkaloid from a marine Streptomyces sp. Organic Letters. 15: 988-91
Yamanaka K, Ryan KS, Gulder TA, et al. (2012) Flavoenzyme-catalyzed atropo-selective N,C-bipyrrole homocoupling in marinopyrrole biosynthesis. Journal of the American Chemical Society. 134: 12434-7
Hughes CC, Kauffman CA, Jensen PR, et al. (2010) Structures, reactivities, and antibiotic properties of the marinopyrroles A-F. The Journal of Organic Chemistry. 75: 3240-50
Hughes CC, Fenical W. (2010) Total synthesis of the ammosamides. Journal of the American Chemical Society. 132: 2528-9
Pangerl M, Hughes CC, Trauner D. (2010) Total synthesis of newbouldine via reductive N-N bond formation Tetrahedron. 66: 6626-6631
Hughes CC, MacMillan JB, Gaudêncio SP, et al. (2009) The ammosamides: Structures of cell cycle modulators from a marine-derived Streptomyces species Angewandte Chemie - International Edition. 48: 725-727
Hughes CC, Prieto-Davo A, Jensen PR, et al. (2008) The marinopyrroles, antibiotics of an unprecedented structure class from a marine Streptomyces sp. Organic Letters. 10: 629-31
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