Stefan Nikolaus Gradl

2005

Dirk Trauner	grad student	2005	UC Berkeley
(I. Development of novel pericyclic reactions for the asymmetric synthesis of cyclopentenones related to the guanacastepenes, and, II. Rational design of tetraphenylporphyrins as blockers of voltage-gated potassium channels.)

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Mathieu S, Gradl SN, Ren L, et al. (2012) Potent and selective aminopyrimidine-based B-Raf inhibitors with favorable physicochemical and pharmacokinetic properties. Journal of Medicinal Chemistry. 55: 2869-81
Trauner D, Miller A, Hughes C, et al. (2007) Synthesis of (-)-Heptemerone B Synfacts. 2007: 0455-0455
Gradl SN, Trauner D. (2007) The Meerwein-Eschenmoser-Claisen Rearrangement The Claisen Rearrangement: Methods and Applications. 367-396
Miller AK, Hughes CC, Kennedy-Smith JJ, et al. (2006) Total synthesis of (-)-heptemerone B and (-)-guanacastepene E. Journal of the American Chemical Society. 128: 17057-62
Liang G, Gradl SN, Trauner D. (2003) Efficient Nazarov cyclizations of 2-alkoxy-1,4-pentadien-3-ones. Organic Letters. 5: 4931-4
Gradl SN, Felix JP, Isacoff EY, et al. (2003) Protein surface recognition by rational design: nanomolar ligands for potassium channels. Journal of the American Chemical Society. 125: 12668-9
Gradl SN, Kennedy-Smith JJ, Kim J, et al. (2002) A Practical Variant of the Claisen-Eschenmoser Rearrangement: Synthesis of Unsaturated Morpholine Amides Synlett. 2002: 0411-0414
Gradl SN, Kennedy-Smith JJ, Kim J, et al. (2002) A practical variant of the Claisen-Eschenmoser rearrangement: Synthesis of unsaturated morpholine amides Synlett. 411-414