John R. Engen

Affiliations: 
Chemistry and Chemical Biology Northeastern University, Boston, MA, United States 
Area:
Bioanalytical chemistry, mass spectrometry, hydrogen/deuterium exchange
Website:
https://neu.hxms.com
Google:
"John R. Engen"
Bio:

Asst. Prof. Chemistry, 2002-2006, University of New Mexico, Albuquerque
Assoc. Prof. Chemistry, 2006-2011, Northeastern University, Boston
Prof. Chemistry, 2011-present, Northeastern University, Boston

Mean distance: 9.82
 
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Publications

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Joseph RE, Amatya N, Fulton DB, et al. (2020) Differential impact of BTK active site inhibitors on the conformational state of full-length BTK. Elife. 9
Engen JR, Botzanowski T, Peterle D, et al. (2020) Developments in Hydrogen/Deuterium Exchange Mass Spectrometry. Analytical Chemistry
Staudt RP, Alvarado JJ, Emert-Sedlak LA, et al. (2020) Structure, function, and inhibitor targeting of HIV-1 Nef-effector kinase complexes. The Journal of Biological Chemistry
Cathcart AM, Bird GH, Wales TE, et al. (2020) Targeting a helix-in-groove interaction between E1 and E2 blocks ubiquitin transfer. Nature Chemical Biology
Vetter CJ, Thorn DC, Wheeler SG, et al. (2020) Cumulative deamidations of the major lens protein γS-crystallin increase its aggregation during unfolding and oxidation. Protein Science : a Publication of the Protein Society
Korshavn KJ, Wales TE, Bird GH, et al. (2020) A redox switch regulates the structure and function of anti-apoptotic BFL-1. Nature Structural & Molecular Biology
Hauseman ZJ, Harvey EP, Newman CE, et al. (2020) Homogeneous Oligomers of Pro-apoptotic BAX Reveal Structural Determinants of Mitochondrial Membrane Permeabilization. Molecular Cell
Harvey EP, Hauseman ZJ, Cohen DT, et al. (2020) Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering. Cell Chemical Biology
Ben-Nun Y, Seo HS, Harvey EP, et al. (2020) Identification of a Structural Determinant for Selective Targeting of HDMX. Structure (London, England : 1993)
Bird GH, Fu A, Escudero S, et al. (2020) Hydrocarbon-stitched Peptide Agonists of Glucagon-Like Peptide-1 Receptor. Acs Chemical Biology
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