David Lee Smith

1974-1984 Chemistry University of Utah, Salt Lake City, UT 
 1984-1994 Medicinal Chemistry Purdue University, West Lafayette, IN, United States 
 1994-2004 Chemistry The University of Nebraska - Lincoln, Lincoln, NE 
Physical chemistry, analytical chemistry, mass spectrometry, hydrogen exchange
"David Smith"
Mean distance: 9.24
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Chen J, Concel VJ, Bhatla S, et al. (2007) Alternative splicing of an rnp-4f mRNA isoform retaining an evolutionarily-conserved 5'-UTR intronic element is developmentally regulated and shown via RNAi to be essential for normal central nervous system development in Drosophila melanogaster. Gene. 399: 91-104
Wang L, Smith DL. (2005) Capsid structure and dynamics of a human rhinovirus probed by hydrogen exchange mass spectrometry. Protein Science : a Publication of the Protein Society. 14: 1661-72
Pan H, Smith DL. (2004) Amide hydrogen exchange/mass spectrometry applied to cooperative protein folding: equilibrium unfolding of Staphylococcus aureus aldolase. Methods in Enzymology. 380: 285-308
Pan H, Raza AS, Smith DL. (2004) Equilibrium and kinetic folding of rabbit muscle triosephosphate isomerase by hydrogen exchange mass spectrometry. Journal of Molecular Biology. 336: 1251-63
Pan H, Smith DL. (2003) Quaternary structure of aldolase leads to differences in its folding and unfolding intermediates. Biochemistry. 42: 5713-21
Wang L, Smith DL. (2003) Downsizing improves sensitivity 100-fold for hydrogen exchange-mass spectrometry. Analytical Biochemistry. 314: 46-53
Wang L, Smith DL. (2002) Probing protein structure and dynamics by hydrogen exchange-mass spectrometry. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. Unit 17.6
Wang L, Pan H, Smith DL. (2002) Hydrogen exchange-mass spectrometry: optimization of digestion conditions. Molecular & Cellular Proteomics : McP. 1: 132-8
Gmeiner WH, Xu I, Horita DA, et al. (2001) Intramolecular binding of a proximal PPII helix to an SH3 domain in the fusion protein SH3Hck : PPIIhGAP. Cell Biochemistry and Biophysics. 35: 115-26
Chen J, Walter S, Horwich AL, et al. (2001) Folding of malate dehydrogenase inside the GroEL-GroES cavity. Nature Structural Biology. 8: 721-8
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