Mark Bathe, Ph.D.

Affiliations: 
2009- Biological Engineering Massachusetts Institute of Technology, Cambridge, MA, United States 
Website:
http://be.mit.edu/directory/mark-bathe
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"Mark Bathe"
Bio:

Professor Bathe is an Associate Professor in the Department of Biological Engineering at MIT, an Associate Member of the Broad Institute of MIT & Harvard, Co-Chair of the MIT New Engineering Education Transformation, and Chair of the MIT Committee on Student Life. Professor Bathe obtained his Doctoral Degree from MIT working in the Departments of Mechanical, Chemical, and Biological Engineering before moving to the University of Munich to carry out his postdoctoral research. He returned to MIT in 2009 to join the faculty in the Department of Biological Engineering, where he runs an interdisciplinary research group focused on the targeted delivery of therapeutic nucleic acids and vaccines, phenotypic profiling of neuronal circuits involved in psychiatric disease, and engineering nucleic acid materials for highly parallel molecular computing and massive data storage.

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Publications

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Wei X, Chen C, Popov AV, et al. (2024) Binding Site Programmable Self-Assembly of 3D Hierarchical DNA Origami Nanostructures. The Journal of Physical Chemistry. A
Gorman J, Hart SM, John T, et al. (2024) Sculpting photoproducts with DNA origami. Chem. 10: 1553-1575
Berleant JD, Banal JL, Rao DK, et al. (2024) Scalable search of massively pooled nucleic acid samples enabled by a molecular database query language. Medrxiv : the Preprint Server For Health Sciences
Chen C, Luo X, Kaplan AEK, et al. (2023) Ultrafast dense DNA functionalization of quantum dots and rods for scalable 2D array fabrication with nanoscale precision. Science Advances. 9: eadh8508
Hart SM, Gorman J, Bathe M, et al. (2023) Engineering Exciton Dynamics with Synthetic DNA Scaffolds. Accounts of Chemical Research
Knappe GA, Wamhoff EC, Bathe M. (2023) Functionalizing DNA origami to investigate and interact with biological systems. Nature Reviews. Materials. 8: 123-138
Parsons MF, Allan MF, Li S, et al. (2023) 3D RNA-scaffolded wireframe origami. Nature Communications. 14: 382
Du RR, Cedrone E, Romanov A, et al. (2022) Innate Immune Stimulation Using 3D Wireframe DNA Origami. Acs Nano
Hart SM, Banal JL, Castellanos MA, et al. (2022) Activating charge-transfer state formation in strongly-coupled dimers using DNA scaffolds. Chemical Science. 13: 13020-13031
Chen C, Wei X, Parsons MF, et al. (2022) Nanoscale 3D spatial addressing and valence control of quantum dots using wireframe DNA origami. Nature Communications. 13: 4935
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