Spiros Kambourakis

Affiliations: 
2000 Michigan State University, East Lansing, MI 
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"Spiros Kambourakis"
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John Wesley Frost grad student 2000 Michigan State
 (Synthesis of value -added chemicals from glucose using chemical and microbial catalysis: Gallic acid, protocatechuic acid, pyrogallol and catechol.)
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Publications

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Dascier D, Kambourakis S, Hua L, et al. (2014) Influence of Cofactor Regeneration Strategies on Preparative-Scale, Asymmetric Carbonyl Reductions by Engineered Escherichia coli. Organic Process Research & Development. 18: 793-800
Magnus NA, Coffey DS, Debaillie AC, et al. (2011) Diarylketone ketoreductase screen and synthesis demonstration to access mglu2 receptor potentiators Organic Process Research and Development. 15: 1377-1381
Schittmayer M, Glieder A, Uhl MK, et al. (2011) Old yellow enzyme-catalyzed dehydrogenation of saturated ketones Advanced Synthesis and Catalysis. 353: 268-274
Weis R, Winkler M, Schittmayer M, et al. (2009) A diversified library of bacterial and fungal bifunctional cytochrome P450 enzymes for drug metabolite synthesis Advanced Synthesis and Catalysis. 351: 2140-2146
Li W, Rozzell D, Kambourakis S, et al. (2009) Biosynthesis of Drug Metabolites Biocatalysis For the Pharmaceutical Industry: Discovery, Development, and Manufacturing. 183-211
Kalaitzakis D, Kambourakis S, Rozzell DJ, et al. (2007) Stereoselective chemoenzymatic synthesis of sitophilate: a natural pheromone Tetrahedron Asymmetry. 18: 2418-2426
Kaluzna IA, Rozzell JD, Kambourakis S. (2006) Corrigendum to "Ketoreductases: stereoselective catalysts for the facile synthesis of chiral alcohols". [Tetrahedron: Asymmetry 16 (2005) 3682] (DOI:10.1016/j.tetasy.2005.10.002) Tetrahedron Asymmetry. 17: 2722
Zhu D, Mukherjee C, Rozzell JD, et al. (2006) A recombinant ketoreductase tool-box. Assessing the substrate selectivity and stereoselectivity toward the reduction of β-ketoesters Tetrahedron. 62: 901-905
Kalaitzakis D, Rozzell JD, Kambourakis S, et al. (2006) A two-step chemoenzymatic synthesis of the natural pheromone (+)-sitophilure utilizing isolated, NADPH-dependent ketoreductases European Journal of Organic Chemistry. 2309-2313
Kalaitzakis D, Rozzell JD, Smonou I, et al. (2006) Synthesis of valuable chiral intermediates by isolated ketoreductases: Application in the synthesis of α-alkyl-β-hydroxy ketones and 1,3-diols Advanced Synthesis and Catalysis. 348: 1958-1969
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