Christopher Abell, Ph.D.

Affiliations: 
1994-1999 Biological Chemistry University of Cambridge, Cambridge, England, United Kingdom 
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Parents

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James Staunton grad student 1979-1982 Cambridge
David E. Cane post-doc 1982-1983 Brown

Children

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Wing Ying Chow research assistant 2005-2006 Cambridge
Michael Webb grad student
Shankar Balasubramanian grad student 1988-1991 Cambridge
Emily J. Parker grad student 1991-1998 Cambridge
Matthew H. Todd grad student 1994-1999 Cambridge
Rebecca M. Myers grad student 1997-2001
Alessio Ciulli grad student 2002-2006 University of Cambridge, United Kingdom
Richard J. Payne grad student 2003-2006 Cambridge
Fleur Marcia Ferguson grad student 2010-2014 Cambridge
Daniel Shiu-Hin Chan grad student 2014-2018
Anthony G Coyne post-doc Cambridge
Sitthivut Charoensutthivarakul post-doc 2017-
Kellie L. Tuck post-doc 2001-2004 Cambridge
Alessio Ciulli post-doc 2006-2009 University of Cambridge, United Kingdom
Rajavel Srinivasan post-doc 2010-2013 Cambridge
Chiara Rose Valenzano post-doc 2010-2013 Cambridge
Dejian Zhou research scientist 2000-2007 Cambridge
Matthew T O Holland research scientist 2019-2020

Collaborators

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Marko Hyvonen collaborator 2004-2020 University of Cambridge (UK) (Computational Biology Tree)
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Publications

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Sabbah M, Mendes V, Vistal RG, et al. (2020) Correction to Fragment-Based Design of InhA Inhibitors. Journal of Medicinal Chemistry
Ribeiro JA, Hammer AJS, Libreros-Z Uacute Ntilde Iga GAES, et al. (2020) Using a fragment-based approach to identify alternative chemical scaffolds targeting dihydrofolate reductase from Mycobacterium tuberculosis. Acs Infectious Diseases
Thomas SE, Whitehouse AJ, Brown K, et al. (2020) Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification. Nucleic Acids Research
Sabbah M, Mendes V, Vistal RG, et al. (2020) Fragment-based design of Mycobacterium tuberculosis InhA inhibitors. Journal of Medicinal Chemistry
Trapero A, Pacitto A, Chan DS, et al. (2019) Covalent inactivation of Mycobacterium thermoresistibile inosine-5'-monophosphate dehydrogenase (IMPDH). Bioorganic & Medicinal Chemistry Letters. 126792
Whitehouse AJ, Libardo MDJ, Kasbekar M, et al. (2019) Targeting of fumarate hydratase from Mycobacterium tuberculosis using allosteric inhibitors with a dimeric-binding mode. Journal of Medicinal Chemistry
Chan DS, Hess J, Shaw E, et al. (2019) Structural Insights into Phosphopantothenoylcysteine Synthetase by Native Ion Mobility-Mass Spectrometry. The Biochemical Journal
Whitehouse A, Thomas SE, Brown KP, et al. (2019) Development of inhibitors against Mycobacterium abscessus tRNA (m1G37) methyltransferase (TrmD) using fragment-based approaches. Journal of Medicinal Chemistry
Thomas SE, Collins P, James RH, et al. (2019) Structure-guided fragment-based drug discovery at the synchrotron: screening binding sites and correlations with hotspot mapping. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 377: 20180422
Bestgen B, Krimm I, Kufareva I, et al. (2019) 2-Aminothiazole derivatives as selective allosteric modulators of the protein kinase CK2. Part 1: Identification of an allosteric binding site. Journal of Medicinal Chemistry
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