K. Dane Wittrup

Affiliations: 
1989-1999 Chemical Engineering University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
 1999- Chemical Engineering and Biological Engineering Massachusetts Institute of Technology, Cambridge, MA, United States 
Website:
https://be.mit.edu/directory/k-dane-wittrup
Google:
"Karl Dane Wittrup"
Bio:

http://kdw-lab.mit.edu/
http://resolver.caltech.edu/CaltechETD:etd-02212007-131607

Mean distance: 10.21
 
SNBCP

Parents

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James E. Bailey grad student 1989 Caltech
 (Plasmid propagation in the yeast Saccaromyces cerevisiae : flow cytometry studies and segregated modeling)

Children

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Camille Z. McAvoy research assistant 2012 MIT
Anne Skaja Robinson grad student (E-Tree)
Eric V. Shusta grad student 1999 UIUC (Microtree)
Sarah J. Bannister grad student 2000 UIUC
Balaji M. Rao grad student 1999-2004 MIT (E-Tree)
Greg Thurber grad student 2008 MIT
Ben Hackel grad student 2009 MIT (Imaging Tree)
Jamie B. Spangler grad student 2011 MIT
Jennifer Rachel Cochran post-doc 2002-2004 MIT (Neurotree)
James A. Van Deventer post-doc 2011-2015 MIT

Collaborators

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Gregory L. Szeto collaborator 2011-2015 (Microtree)
BETA: Related publications

Publications

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Mehta NK, Pradhan RV, Soleimany AP, et al. (2020) Pharmacokinetic tuning of protein-antigen fusions enhances the immunogenicity of T-cell vaccines. Nature Biomedical Engineering
Ma L, Dichwalkar T, Chang JYH, et al. (2019) Enhanced CAR-T cell activity against solid tumors by vaccine boosting through the chimeric receptor. Science (New York, N.Y.). 365: 162-168
Momin N, Mehta NK, Bennett NR, et al. (2019) Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy. Science Translational Medicine. 11
Dréau D, Moore LJ, Wu M, et al. (2019) Combining the Specific Anti-MUC1 Antibody TAB004 and Lip-MSA-IL-2 Limits Pancreatic Cancer Progression in Immune Competent Murine Models of Pancreatic Ductal Adenocarcinoma. Frontiers in Oncology. 9: 330
Rothschilds A, Tzeng A, Mehta NK, et al. (2019) Order of administration of combination cytokine therapies can decouple toxicity from efficacy in syngeneic mouse tumor models. Oncoimmunology. 8: e1558678
Angelini A, Miyabe Y, Newsted D, et al. (2018) Directed evolution of broadly crossreactive chemokine-blocking antibodies efficacious in arthritis. Nature Communications. 9: 1461
Kelly RL, Le D, Zhao J, et al. (2018) Reduction of Nonspecificity Motifs in Synthetic Antibody Libraries. Journal of Molecular Biology. 430: 119-130
Green DJ, O'Steen S, Lin Y, et al. (2017) CD38 bispecific antibody pretargeted radioimmunotherapy for multiple myeloma and other B cell malignancies. Blood
Kelly RL, Zhao J, Le D, et al. (2017) Nonspecificity in a nonimmune human scFv repertoire. Mabs. 0
Wittrup KD. (2017) Antitumor Antibodies Can Drive Therapeutic T Cell Responses. Trends in Cancer. 3: 615-620
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