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Gregory Douglas Cuny

Affiliations: 
1992 Pharmacological and Pharmaceutical Sciences University of Houston, Houston, TX, United States 
Area:
medicinal chemistry
Website:
http://www.uh.edu/pharmacy/directory-home/pps-faculty/greg-cuny/
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"Gregory Douglas Cuny"
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Stephen L. Buchwald grad student 1992 MIT
 (The utilisation of zirconium intermediates and the development of hydroformylatlon processes in organic synthesis)
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Publications

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Chen H, Lye MF, Gorgulla C, et al. (2023) A small molecule exerts selective antiviral activity by targeting the human cytomegalovirus nuclear egress complex. Plos Pathogens. 19: e1011781
Modi G, Marqus GM, Vippila MR, et al. (2021) The Enzymatic Activity of Inosine 5'-Monophosphate Dehydrogenase May Not Be a Vulnerable Target for Infections. Acs Infectious Diseases
Nikhar S, Siokas I, Schlicher L, et al. (2021) Design of pyrido[2,3-d]pyrimidin-7-one inhibitors of receptor interacting protein kinase-2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling. European Journal of Medicinal Chemistry. 215: 113252
Lee S, Ku A, Rao Vippila M, et al. (2020) Mycophenolic anilides as broad specificity inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitors. Bioorganic & Medicinal Chemistry Letters. 127543
Cuny GD, Degterev A. (2020) RIPK protein kinase family: Atypical lives of typical kinases. Seminars in Cell & Developmental Biology
Suebsuwong C, Dai B, Pinkas DM, et al. (2020) Receptor-interacting protein kinase 2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling inhibitors based on a 3,5-diphenyl-2-aminopyridine scaffold. European Journal of Medicinal Chemistry. 200: 112417
Pawlowic MC, Somepalli M, Sateriale A, et al. (2019) Genetic ablation of purine salvage in reveals nucleotide uptake from the host cell. Proceedings of the National Academy of Sciences of the United States of America
Ali G, Cuny GD. (2019) An efficient synthesis of an 8-phenoxy aporphine derivative utilizing mono-ligated palladium ortho-phenol arylation Tetrahedron. 75: 4318-4324
Kearney SE, Zahoránszky-Kőhalmi G, Brimacombe KR, et al. (2018) Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space. Acs Central Science. 4: 1727-1741
Jiang JK, Huang X, Shamim K, et al. (2018) Discovery of 3-(4-sulfamoylnaphthyl)pyrazolo[1,5-a]pyrimidines as potent and selective ALK2 inhibitors. Bioorganic & Medicinal Chemistry Letters
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