Hank Michael Petrassi
Affiliations: | 2001 | Scripps Research Institute, La Jolla, La Jolla, CA, United States |
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"Hank Petrassi"Mean distance: 8.73 | S | N | B | C | P |
Parents
Sign in to add mentor| Jeffery W. Kelly | grad student | 2001 | Scripps Institute | |
| (Design and synthesis of inhibitors of transthyretin amyloid fibril formation.) | ||||
| Peter G. Schultz | post-doc | 2001- | Scripps Research Institute | |
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Publications
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| Liu YA, Jin Q, Zou Y, et al. (2020) Selective DYRK1A Inhibitor for the Treatment of Type 1 Diabetes: Discovery of 6-Azaindole Derivative GNF2133. Journal of Medicinal Chemistry |
| Bakowski MA, Shiroodi RK, Liu R, et al. (2019) Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections. Science Translational Medicine. 11 |
| Janes J, Young ME, Chen E, et al. (2018) The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis. Proceedings of the National Academy of Sciences of the United States of America. 115: 10750-10755 |
| Choi SH, Mahankali M, Lee SJ, et al. (2017) Targeted disruption of Myc-Max oncoprotein complex by a small molecule. Acs Chemical Biology |
| Petrassi HM, Johnson SM, Purkey HE, et al. (2005) Potent and selective structure-based dibenzofuran inhibitors of transthyretin amyloidogenesis: kinetic stabilization of the native state. Journal of the American Chemical Society. 127: 6662-71 |
| Johnson SM, Petrassi HM, Palaninathan SK, et al. (2005) Bisaryloxime ethers as potent inhibitors of transthyretin amyloid fibril formation. Journal of Medicinal Chemistry. 48: 1576-87 |
| McCammon MG, Scott DJ, Keetch CA, et al. (2002) Screening transthyretin amyloid fibril inhibitors: characterization of novel multiprotein, multiligand complexes by mass spectrometry. Structure (London, England : 1993). 10: 851-63 |
| Oza VB, Smith C, Raman P, et al. (2002) Synthesis, structure, and activity of diclofenac analogues as transthyretin amyloid fibril formation inhibitors. Journal of Medicinal Chemistry. 45: 321-32 |
| Jiang X, Smith CS, Petrassi HM, et al. (2001) An engineered transthyretin monomer that is nonamyloidogenic, unless it is partially denatured. Biochemistry. 40: 11442-52 |
| Petrassi HM, Sharpless KB, Kelly JW. (2001) The copper-mediated cross-coupling of phenylboronic acids and N-hydroxyphthalimide at room temperature: synthesis of aryloxyamines. Organic Letters. 3: 139-42 |