Emily J. Parker, Ph.D.

Affiliations: 
1991-1998 Chemistry University of Cambridge, Cambridge, England, United Kingdom 
 1998-2006 Massey University, Palmerston North, Manawatu-Wanganui, New Zealand 
 2006- Biomolecular Interaction Centre University of Canterbury, New Zealand, Christchurch, Canterbury, New Zealand 
Area:
Bioorganic
Website:
http://www.chem.canterbury.ac.nz/people/parker.shtml
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Publications

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Jiao W, Fan Y, Blackmore NJ, et al. (2020) A single amino acid substitution uncouples catalysis and allostery in an essential biosynthetic enzyme in Mycobacterium tuberculosis. The Journal of Biological Chemistry
Jiao W, Mittelstädt G, Moggré GJ, et al. (2019) Hinge Twists and Population Shifts Deliver Regulated Catalysis for ATP-PRT in Histidine Biosynthesis. Biophysical Journal
Bai Y, Lang EJM, Nazmi AR, et al. (2019) Domain cross-talk within a bifunctional enzyme provides catalytic and allosteric functionality in the biosynthesis of aromatic amino acids. The Journal of Biological Chemistry
Sterritt OW, Lang EJM, Kessans SA, et al. (2018) The short-form type II DAH7PS from , associated with phenazine biosynthesis, suggests reclassification of type II enzymes. Bioscience Reports
Heikal A, Nakatani Y, Jiao W, et al. (2018) 'Tethering' fragment-based drug discovery to identify inhibitors of the essential respiratory membrane protein type II NADH dehydrogenase. Bioorganic & Medicinal Chemistry Letters
Petri J, Shimaki Y, Jiao W, et al. (2018) Structure of the NDH-2 - HQNO inhibited complex provides molecular insight into quinone-binding site inhibitors. Biochimica Et Biophysica Acta
Sterritt O, Kessans SA, Jameson GB, et al. (2018) A pseudo-isostructural type II DAH7PS enzyme from Pseudomonas aeruginosa: alternative evolutionary strategies to control shikimate pathway flux. Biochemistry
Fan Y, Cross PJ, Jameson GB, et al. (2018) Exploring modular allostery via interchangeable regulatory domains. Proceedings of the National Academy of Sciences of the United States of America
Mittelstädt G, Jiao W, Livingstone E, et al. (2017) A dimeric catalytic core relates the short and long forms of ATP-phosphoribosyltransferase. The Biochemical Journal
Evans GL, Furkert DP, Abermil N, et al. (2017) Datasets, processing and refinement details for Mtb-AnPRT: inhibitor structures with various space groups. Data in Brief. 15: 1019-1029
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