Richard N. Armstrong, Ph.D.

1995-2015 Chemistry Vanderbilt University, Nashville, TN 
Biochemistry, Mechanistic Enzymology
"Richard Armstrong"
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Peter R Panizzi grad student 1997-1999 Vanderbilt
Christopher L. Rife grad student 2002 Vanderbilt
Simona G. Codreanu grad student 2003 Vanderbilt
Rachel P. Rigsby grad student 2005 Vanderbilt
Megan C. Branch grad student 2011 Vanderbilt
Edward B. Prage grad student 2012 Vanderbilt
Maria Merced Malabanan post-doc 2014-2015 Vanderbilt (Crystallography Tree)
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Spahiu L, Ålander J, Ottosson-Wadlund A, et al. (2017) Global Kinetic Mechanism of Microsomal Glutathione Transferase 1, insights into dynamic enzyme activation. Biochemistry
Raouf J, Rafique N, Goodman MC, et al. (2016) Arg126 and Asp49 Are Essential for the Catalytic Function of Microsomal Prostaglandin E2 Synthase 1 and Ser127 Is Not. Plos One. 11: e0163600
Dong GQ, Calhoun S, Fan H, et al. (2014) Prediction of substrates for glutathione transferases by covalent docking. Journal of Chemical Information and Modeling. 54: 1687-99
Mashiyama ST, Malabanan MM, Akiva E, et al. (2014) Large-scale determination of sequence, structure, and function relationships in cytosolic glutathione transferases across the biosphere. Plos Biology. 12: e1001843
Thompson MK, Keithly ME, Goodman MC, et al. (2014) Structure and function of the genomically encoded fosfomycin resistance enzyme, FosB, from Staphylococcus aureus. Biochemistry. 53: 755-65
Thompson MK, Keithly ME, Harp J, et al. (2013) Structural and chemical aspects of resistance to the antibiotic fosfomycin conferred by FosB from Bacillus cereus. Biochemistry. 52: 7350-62
Lamers AP, Keithly ME, Kim K, et al. (2012) Synthesis of bacillithiol and the catalytic selectivity of FosB-type fosfomycin resistance proteins. Organic Letters. 14: 5207-9
Prage EB, Morgenstern R, Jakobsson PJ, et al. (2012) Observation of two modes of inhibition of human microsomal prostaglandin E synthase 1 by the cyclopentenone 15-deoxy-Δ(12,14)-prostaglandin J(2). Biochemistry. 51: 2348-56
Preininger AM, Kaya AI, Gilbert JA, et al. (2012) Myristoylation exerts direct and allosteric effects on Gα conformation and dynamics in solution. Biochemistry. 51: 1911-24
Prage EB, Pawelzik SC, Busenlehner LS, et al. (2011) Location of inhibitor binding sites in the human inducible prostaglandin E synthase, MPGES1. Biochemistry. 50: 7684-93
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