Thomas Edward Wales
Affiliations: | 2006- | Chemistry and Chemical Biology | Northeastern University, Boston, MA, United States |
Area:
Bioanalytical ChemistryGoogle:
"Thomas Wales"Mean distance: 9.13 | S | N | B | C | P |
Parents
Sign in to add mentorMichael C. Fitzgerald | grad student | 1998-2003 | Duke | |
(Total chemical synthesis and biophysical characterization of backbone-modified protein analogues.) | ||||
John R. Engen | research scientist | 2004- | Northeastern University |
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Publications
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Joseph RE, Wales TE, Jayne S, et al. (2024) Impact of the clinically approved BTK inhibitors on the conformation of full-length BTK and analysis of the development of BTK resistance mutations in chronic lymphocytic leukemia. Elife. 13 |
Selzer AM, Gerlach G, Gonzalez-Areizaga G, et al. (2024) An SH3-binding allosteric modulator stabilizes the global conformation of the AML-associated Src-family kinase, Hck. The Journal of Biological Chemistry. 108088 |
Rennella E, Henry C, Dickson CJ, et al. (2024) Dynamic conformational equilibria in the active states of KRAS and NRAS. Rsc Chemical Biology |
Wales TE, Pajak A, Roeselová A, et al. (2024) Resolving chaperone-assisted protein folding on the ribosome at the peptide level. Nature Structural & Molecular Biology |
Woo JR, Bae SH, Wales TE, et al. (2024) The serine phosphorylations in the IRS-1 PIR domain abrogate IRS-1 and IR interaction. Proceedings of the National Academy of Sciences of the United States of America. 121: e2401716121 |
McHenry MW, Shi P, Camara CM, et al. (2024) Covalent inhibition of pro-apoptotic BAX. Nature Chemical Biology |
Lin DY, Kueffer LE, Juneja P, et al. (2024) Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. Elife. 12 |
Joseph RE, Wales TE, Jayne S, et al. (2023) Impact of the clinically approved BTK inhibitors on the conformation of full-length BTK and analysis of the development of BTK resistance mutations in chronic lymphocytic leukemia. Biorxiv : the Preprint Server For Biology |
Lin DY, Kueffer LE, Juneja P, et al. (2023) Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. Biorxiv : the Preprint Server For Biology |
A M, Wales TE, Zhou H, et al. (2023) Irisin acts through its integrin receptor in a two-step process involving extracellular Hsp90α. Molecular Cell. 83: 1903-1920.e12 |