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Lawrence P. Wackett

1987- Biochemistry, Molecular Biology and Biophysics University of Minnesota, Twin Cities, Minneapolis, MN 
microbial biodegradation, biocatalysis
"Lawrence Wackett"
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David T. Gibson grad student 1984 UT Austin
 (Aromatic hydrocarbon metabolism by fungal and bacterial enzymes)
Christopher T. Walsh post-doc 1984-1987 MIT


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Betsy Milagros Martinez-Vaz grad student 2001 UMN
Jennifer Lynn Seffernick grad student 2001 UMN
Michelle Lynn Wagner grad student 2001 UMN
Charlotte Rosendahl Pedersen grad student 2003 UMN
Kannika Sajjaphan grad student 2003 UMN
Anthony Gerald Dodge grad student 2008 UMN
David John Sukovich grad student 2010 UMN
Janice Alina Frias grad student 2011 UMN
Stephan Mary Cameron grad student 2013 UMN
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Tassoulas LJ, Robinson A, Martinez-Vaz B, et al. (2021) Filling in the Gaps in Metformin Biodegradation: A New Enzyme and a Metabolic Pathway for Guanylurea. Applied and Environmental Microbiology
Tassoulas LJ, Elias MH, Wackett LP. (2020) Discovery of an ultra-specific triuret hydrolase (TrtA) establishes the triuret biodegradation pathway. The Journal of Biological Chemistry
Robinson SL, Terlouw BR, Smith MD, et al. (2020) Global analysis of adenylate-forming enzymes reveals β-lactone biosynthesis pathway in pathogenic . The Journal of Biological Chemistry
Wackett LP, Robinson SL. (2020) The ever-expanding limits of enzyme catalysis and biodegradation: polyaromatic, polychlorinated, polyfluorinated, and polymeric compounds. The Biochemical Journal. 477: 2875-2891
Schneider NO, Tassoulas LJ, Zeng D, et al. (2020) Solving the conundrum: Widespread proteins annotated for urea metabolism in bacteria are carboxyguanidine deiminases mediating nitrogen assimilation from guanidine. Biochemistry
Smith MD, Robinson SL, Molomjamts M, et al. (2020) Assay Reveals Microbial OleA Thiolases Initiating Hydrocarbon and β-Lactone Biosynthesis. Mbio. 11
Aukema KG, Tassoulas LJ, Robinson SL, et al. (2019) Cyanuric Acid Biodegradation via Biuret: Physiology, Taxonomy and Geospatial Distribution. Applied and Environmental Microbiology
Hernández NE, Hansen WA, Zhu D, et al. (2019) Stimulus-responsive self-assembly of protein-based fractals by computational design. Nature Chemistry
Shi K, Cho S, Aukema KG, et al. (2019) Crystal structures of Moorella thermoacetica cyanuric acid hydrolase reveal conformational flexibility and asymmetry important for catalysis. Plos One. 14: e0216979
Robinson SL, Christenson JK, Richman JE, et al. (2019) Mechanism of a Standalone β-Lactone Synthetase: New Continuous Assay for a Widespread ANL Superfamily Enzyme. Chembiochem : a European Journal of Chemical Biology
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