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William C. Shakespeare

Affiliations: 
1986-1991 Chemistry University of New Hampshire, Durham, NH, United States 
Website:
http://www.ariad.com/wshakespeare
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Richard P. Johnson grad student 1986-1991 UNH
 (Asymmetric photochemistry. : Exploratory and mechanistic studies on the triplet sensitized vapor phase photochemistry of allenes. Developments in the synthesis of strained cyclic cumulenes.)
Amos B. Smith, III post-doc 1991-1993 Penn
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HIRSCHMANN R, SPRENGELER PA, KAWASAKI T, et al. (2010) ChemInform Abstract: The First Design and Synthesis of a Steroidal Peptidomimetic. The Potential Value of Peptidomimetics in Elucidating the Bioactive Conformation of Peptide Ligands. Cheminform. 24: no-no
Hirschmann R, Hynes J, Cichy-Knight MA, et al. (1998) Modulation of receptor and receptor subtype affinities using diastereomeric and enantiomeric monosaccharide scaffolds as a means to structural and biological diversity. A new route to ether synthesis. Journal of Medicinal Chemistry. 41: 1382-91
Hirschmann R, Nicolaou KC, Pietranico S, et al. (1993) De novo design and synthesis of somatostatin non-peptide peptidomimetics utilizing .beta.-D-glucose as a novel scaffolding Journal of the American Chemical Society. 115: 12550-12568
Hirschmann R, Sprengeler PA, Kawasaki T, et al. (1993) The versatile steroid nucleus: Design and synthesis of a peptidomimetic employing this novel scaffold. Tetrahedron. 49: 3665-3676
Hirschmann R, Sprengeler PA, Kawasaki T, et al. (1992) The first design and synthesis of a steroidal peptidomimetic. The potential value of peptidomimetics in elucidating the bioactive conformation of peptide ligands Journal of the American Chemical Society. 114: 9699-9701
Shakespeare WC, Johnson RP. (1991) Ab initio study of hydrogen abstraction by triplet cyclopropylidene and planar triplet allene Journal of Organic Chemistry. 56: 6377-6379
Stierman TJ, Shakespeare WC, Johnson RP. (1990) Cumulene photochemistry: Substituent effects on the mechanism of 1,2-cyclononadiene photochemistry Journal of Organic Chemistry. 55: 1043-1047
Shakespeare WC, Johnson RP. (1990) 1,2,3-cyclohexatriene and cyclohexen-3-yne: Two new highly strained C6H6 isomers Journal of the American Chemical Society. 112: 8578-8579
Tolbert LM, Islam MN, Johnson RP, et al. (1990) Carbanion photochemistry: A new photochemical route to strained cyclic allenes Journal of the American Chemical Society. 112: 6416-6417
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