Mehmet Can

Affiliations: 
University of Rochester, Rochester, NY 
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"Mehmet Can"
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Kara L. Bren grad student 2007-2012 Rochester
 (Factors affecting the heme electronic structure of proteins with heme c)
Stephen W. Ragsdale post-doc 2012-2018 University of Michigan Medical School Ann Arbor
 (Investigation of the mechanisms and applications of the key enzymes involved in an unusual pathway of CO2 fixation: Wood-Ljungdahl Pathway - Reductive Acetyl Coenzyme A Pathway)
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Publications

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Wiley S, Griffith C, Eckert P, et al. (2024) An alcove at the acetyl-CoA synthase nickel active site is required for productive substrate CO binding and anaerobic carbon fixation. The Journal of Biological Chemistry. 107503
Can M, Abernathy MJ, Wiley S, et al. (2023) Characterization of Methyl- and Acetyl-Ni Intermediates in Acetyl CoA Synthase Formed during Anaerobic CO and CO Fixation. Journal of the American Chemical Society
Cohen SE, Can M, Wittenborn EC, et al. (2020) Crystallographic Characterization of the Carbonylated A-Cluster in Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase. Acs Catalysis. 10: 9741-9746
Cohen SE, Brignole EJ, Wittenborn EC, et al. (2020) Negative-Stain Electron Microscopy Reveals Dramatic Structural Rearrangements in Ni-Fe-S-Dependent Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase. Structure (London, England : 1993)
Cohen SE, Can M, Wittenborn EC, et al. (2020) Crystallographic Characterization of the Carbonylated A-Cluster in Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase Acs Catalysis. 10: 9741-9746
Zhang L, Can M, Ragsdale SW, et al. (2018) Fast and Selective Photoreduction of CO to CO Catalyzed by a Complex of Carbon Monoxide Dehydrogenase, TiO, and Ag Nanoclusters. Acs Catalysis. 8: 2789-2795
Burton R, Can M, Esckilsen D, et al. (2018) Production and properties of enzymes that activate and produce carbon monoxide. Methods in Enzymology. 613: 297-324
Chen PY, Aman H, Can M, et al. (2018) Binding site for coenzyme A revealed in the structure of pyruvate:ferredoxin oxidoreductase from. Proceedings of the National Academy of Sciences of the United States of America
Chen PY, Aman H, Can M, et al. (2018) Binding site for coenzyme A revealed in the structure of pyruvate:ferredoxin oxidoreductase from Moorella thermoacetica Proceedings of the National Academy of Sciences of the United States of America. 115: 3846-3851
Pierce E, Mansoorabadi SO, Can M, et al. (2017) Properties of intermediates in the catalytic cycle of oxalate oxidoreductase and its suicide inactivation by pyruvate. Biochemistry
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