P. Aru Hill

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2008 University of Pennsylvania, Philadelphia, PA, United States 
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Ivan J. Dmochowski grad student 2008 Penn
 (Synthesis of functionalized cryptophane-A derivatives and assessment of their xenon-binding properties for the construction of hyperpolarized xenon-129 biosensors.)
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Publications

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Bai Y, Hill PA, Dmochowski IJ. (2012) Utilizing a water-soluble cryptophane with fast xenon exchange rates for picomolar sensitivity NMR measurements. Analytical Chemistry. 84: 9935-41
Taratula O, Hill PA, Bai Y, et al. (2011) Shorter synthesis of trifunctionalized cryptophane-A derivatives. Organic Letters. 13: 1414-7
Khan NS, Perez-Aguilar JM, Kaufmann T, et al. (2011) Multiple hindered rotators in a gyroscope-inspired tribenzylamine hemicryptophane. The Journal of Organic Chemistry. 76: 1418-24
Taratula O, Dmochowski IJ, Hill PA, et al. (2011) Crystallization of Cryptophane-A and Cryptophane-A Derivatives with and without Encapsulated Guests Protocol Exchange
Taratula O, Hill PA, Khan NS, et al. (2010) Crystallographic observation of 'induced fit' in a cryptophane host-guest model system. Nature Communications. 1: 148
Hill PA, Wei Q, Troxler T, et al. (2009) Substituent effects on xenon binding affinity and solution behavior of water-soluble cryptophanes. Journal of the American Chemical Society. 131: 3069-77
Chambers JM, Hill PA, Aaron JA, et al. (2009) Cryptophane xenon-129 nuclear magnetic resonance biosensors targeting human carbonic anhydrase. Journal of the American Chemical Society. 131: 563-9
Hill PA, Wei Q, Eckenhoff RG, et al. (2007) Thermodynamics of xenon binding to cryptophane in water and human plasma. Journal of the American Chemical Society. 129: 9262-3
Hill PA, Wei Q, Eckenhoff RG, et al. (2007) Thermodynamics of Xenon Binding to Cryptophane in Water and Human Plasma [J. Am.Chem. Soc.2007,129, 9262−9263]. Journal of the American Chemical Society. 129: 11662-11662
Wei Q, Seward GK, Hill PA, et al. (2006) Designing 129Xe NMR biosensors for matrix metalloproteinase detection. Journal of the American Chemical Society. 128: 13274-83
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